5632-52-0

• 常用中文名：Clofenciclan
• 常用英文名：Clofenciclan
• CAS号：5632-52-0
• 分子式：C₁₈H₂₈ClNO
• 分子量：309.87400
• 发布时间：2017-07-17 08:33:19
• 更新时间：2024-01-06 11:23:00

名称

• 英文名: 2-[1-(4-chlorophenyl)cyclohexyl]oxy-N,N-diethylethanamine
• 英文别名: Veritan; Clofencician; clofenciclan; KSW 786; Chlorphencyclane; Tonoquil; Chlorphencyclan

物化性质

• 密度: 1.06g/cm3
• 沸点: 394.9ºC at 760mmHg
• 分子式: C₁₈H₂₈ClNO
• 分子量: 309.87400
• 闪点: 192.6ºC
• 精确质量: 309.18600
• PSA: 12.47000
• LogP: 4.85780
• 折射率: 1.533

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : YE1127000 CHEMICAL NAME : Triethylamine, 2-((1-(p-chlorophenyl)cyclohexyl)oxy)- CAS REGISTRY NUMBER : 5632-52-0 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C18-H28-Cl-N-O MOLECULAR WEIGHT : 309.92 WISWESSER LINE NOTATION : L6TJ AO2N2&2 AR DG HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 142 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - other changes REFERENCE : ARPMAS Archiv der Pharmazie (Weinheim, Germany) (VCH Pub., Inc., 303 NW 12th Ave., Deerfield Beach, FL 33441) V.51-261, 1835-1923; V.305- 1972- Volume(issue)/page/year: 313,129,1980

合成路线

17380-83-5 100-35-6 ~% 5632-52-0

文献：Stach,K.; Winter,W. Arzneimittel Forschung, 1962 , vol. 12, p. 25 - 29