57144-56-6

• 常用中文名：异洛芬
• 常用英文名：Isoprofen
• CAS号：57144-56-6
• 分子式：C₁₅H₂₀O₂
• 分子量：232.31800
• 发布时间：2018-09-24 15:42:29
• 更新时间：2024-01-14 16:00:52

名称

• 中文名: 异洛芬
• 英文名: 2-(2-propan-2-yl-2,3-dihydro-1H-inden-5-yl)propanoic acid
• 英文别名: 2-isopropyl-a-methyl-5-indanacetic acid; UP 517-03; Isoprofen

物化性质

• 密度: 1.078g/cm3
• 沸点: 361.7ºC at 760mmHg
• 分子式: C₁₅H₂₀O₂
• 分子量: 232.31800
• 闪点: 258.6ºC
• 精确质量: 232.14600
• PSA: 37.30000
• LogP: 3.24550
• 折射率: 1.544

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NK3850100 CHEMICAL NAME : 5-Indanacetic acid, 2-isopropyl-alpha-methyl- CAS REGISTRY NUMBER : 57144-56-6 LAST UPDATED : 199406 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C15-H20-O2 MOLECULAR WEIGHT : 232.35 WISWESSER LINE NOTATION : L56T&J CY1&1 GY1&VQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1500 mg/kg TOXIC EFFECTS : Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 30,1549,1980 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1050 mg/kg TOXIC EFFECTS : Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 30,1549,1980

合成路线

57144-60-2 ~% 57144-56-6

文献：Hexachimie Societe Anonyme Patent: US4166131 A1, 1979 ;

57144-61-3 ~% 57144-56-6

文献：Hexachimie Societe Anonyme Patent: US4166131 A1, 1979 ;