137719-36-9

• 常用中文名：4-amino-1-[(2R,5S)-5-(hydroxymethyl)thiolan-2-yl]pyrimidin-2-one
• 常用英文名：4-amino-1-[(2R,5S)-5-(hydroxymethyl)thiolan-2-yl]pyrimidin-2-one
• CAS号：137719-36-9
• 分子式：C₉H₁₃N₃O₂S
• 分子量：227.28300
• 发布时间：2017-09-19 12:28:20
• 更新时间：2024-01-10 11:21:32

名称

• 英文名: 4-amino-1-[(2R,5S)-5-(hydroxymethyl)thiolan-2-yl]pyrimidin-2-one
• 英文别名: 2',3'-Dideoxy-4'-thiocytosine; Thio-DDC; 4'-Thio-2',3'-dideoxycytidine; 2',3'-dideoxy-4'-thiocytidine

物化性质

• 密度: 1.6g/cm3
• 沸点: 444.5ºC at 760mmHg
• 分子式: C₉H₁₃N₃O₂S
• 分子量: 227.28300
• 闪点: 222.7ºC
• 精确质量: 227.07300
• PSA: 107.43000
• LogP: 0.55440
• 蒸汽压: 9.03E-10mmHg at 25°C
• 折射率: 1.742

合成路线

137819-77-3 ~88% 137719-36-9

文献：Secrist, John A.; Riggs, Robert M.; Tiwari, Kamal N.; Montgomery, John A. Journal of Medicinal Chemistry, 1992 , vol. 35, # 3 p. 533 - 538

185303-82-6 ~% 137719-36-9

文献：Rassu, Gloria; Zanardi, Franca; Battistini, Lucia; Gaetani, Enrico; Casiraghi, Giovanni Journal of Medicinal Chemistry, 1997 , vol. 40, # 2 p. 168 - 180

185303-83-7 ~% 137719-36-9

文献：Rassu, Gloria; Zanardi, Franca; Battistini, Lucia; Gaetani, Enrico; Casiraghi, Giovanni Journal of Medicinal Chemistry, 1997 , vol. 40, # 2 p. 168 - 180

137719-23-4 ~% 137719-36-9

文献：Secrist, John A.; Riggs, Robert M.; Tiwari, Kamal N.; Montgomery, John A. Journal of Medicinal Chemistry, 1992 , vol. 35, # 3 p. 533 - 538