144881-48-1

• 常用中文名：5-[[4-(2-ethoxyphenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine
• 常用英文名：5-[[4-(2-ethoxyphenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine
• CAS号：144881-48-1
• 分子式：C₁₆H₂₄N₄O₂
• 分子量：304.38700
• 发布时间：2016-09-08 16:05:58
• 更新时间：2024-07-23 10:05:58

名称

• 英文名: 5-[[4-(2-ethoxyphenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine

物化性质

• 密度: 1.26g/cm3
• 沸点: 462.7ºC at 760mmHg
• 分子式: C₁₆H₂₄N₄O₂
• 分子量: 304.38700
• 闪点: 233.6ºC
• 精确质量: 304.19000
• PSA: 60.82000
• LogP: 1.56190
• 蒸汽压: 9.68E-09mmHg at 25°C
• 折射率: 1.618

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : RP6746500 CHEMICAL NAME : 2-Oxazolamine, 4,5-dihydro-5-((4-(4-methoxyphenyl)-3-methyl-1-pipera zinyl)methyl)- CAS REGISTRY NUMBER : 144881-48-1 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C16-H24-N4-O2 MOLECULAR WEIGHT : 304.44 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 524 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 27,437,1992

合成路线

35947-12-7 ~% 144881-48-1

文献：Bosc; Jarry; Carpy; Panconi; Descas European Journal of Medicinal Chemistry, 1992 , vol. 27, # 5 p. 437 - 442

1026400-08-7 ~% 144881-48-1

文献：Bosc; Jarry; Carpy; Panconi; Descas European Journal of Medicinal Chemistry, 1992 , vol. 27, # 5 p. 437 - 442

19981-17-0 1026400-08-7 ~9% 144881-48-1

文献：Bosc; Jarry; Carpy; Panconi; Descas European Journal of Medicinal Chemistry, 1992 , vol. 27, # 5 p. 437 - 442

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