78313-59-4

• 常用中文名：5-[[5-hydroxy-4-(methoxymethyl)-6-methyl-pyridin-3-yl]methyldisulfanyl methyl]-4-(methoxymethyl)-2-methyl-pyridin-3-ol dihydrochloride
• 常用英文名：5-[[5-hydroxy-4-(methoxymethyl)-6-methyl-pyridin-3-yl]methyldisulfanyl methyl]-4-(methoxymethyl)-2-methyl-pyridin-3-ol dihydrochloride
• CAS号：78313-59-4
• 分子式：C₁₈H₂₆Cl₂N₂O₄S₂
• 分子量：469.44600
• 发布时间：2016-05-06 19:34:09
• 更新时间：2024-03-04 19:41:41

名称

• 英文名: 5-[[[5-hydroxy-4-(methoxymethyl)-6-methylpyridin-3-yl]methyldisulfanyl]methyl]-4-(methoxymethyl)-2-methylpyridin-3-ol,dihydrochloride

物化性质

• 沸点: 652.6ºC at 760 mmHg
• 分子式: C₁₈H₂₆Cl₂N₂O₄S₂
• 分子量: 469.44600
• 闪点: 348.5ºC
• 精确质量: 468.07100
• PSA: 148.80000
• LogP: 5.29620
• 储存条件: 库房通风低温干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UU7714700 CHEMICAL NAME : 3-Pyridinol, 5,5'-(dithiodimethylene)bis(4-methoxymethyl-2-methyl- , dihydrochloride CAS REGISTRY NUMBER : 78313-59-4 LAST UPDATED : 198609 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C18-H24-N2-O4-S2.2Cl-H MOLECULAR WEIGHT : 469.48 WISWESSER LINE NOTATION : T6NJ B1 CQ D1O1 E1SS1- ET6NJ B1 CQ D1O1 &GH 2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1450 mg/kg TOXIC EFFECTS : Behavioral - hallucinations, distorted perceptions Behavioral - changes in motor activity (specific assay) REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 15,79,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 434 mg/kg TOXIC EFFECTS : Behavioral - hallucinations, distorted perceptions Behavioral - changes in motor activity (specific assay) REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 15,79,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 111 mg/kg TOXIC EFFECTS : Behavioral - hallucinations, distorted perceptions Behavioral - changes in motor activity (specific assay) REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 15,79,1981

合成路线

3131-27-9 ~% 78313-59-4

文献：Kovler, M. A.; Avakumov, V. M.; Lobanova, M. L.; Alekseeva, Zh. P.; Zhukova, Z. N.; et al. Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 2 p. 79 - 81 Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 2 p. 22 - 24

78313-60-7 ~% 78313-59-4

文献：Kovler, M. A.; Avakumov, V. M.; Lobanova, M. L.; Alekseeva, Zh. P.; Zhukova, Z. N.; et al. Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 2 p. 79 - 81 Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 2 p. 22 - 24