76298-68-5

• 常用中文名：2H-Pyrazolo(4,3-c)quinoline, 3,3a,4,5-tetrahydro-2-acetyl-5-((4-methyl phenyl)sulfonyl)-3-phenyl-, cis-
• 常用英文名：2H-Pyrazolo(4,3-c)quinoline, 3,3a,4,5-tetrahydro-2-acetyl-5-((4-methyl phenyl)sulfonyl)-3-phenyl-, cis-
• CAS号：76298-68-5
• 分子式：C₂₅H₂₃N₃O₃S
• 分子量：445.53300
• 发布时间：2016-06-07 15:40:35
• 更新时间：2024-01-10 16:45:06

名称

• 英文名: 1-[(3S,3aR)-5-(4-methylphenyl)sulfonyl-3-phenyl-3a,4-dihydro-3H-pyrazolo[4,3-c]quinolin-2-yl]ethanone

物化性质

• 密度: 1.33g/cm3
• 沸点: 620.8ºC at 760 mmHg
• 分子式: C₂₅H₂₃N₃O₃S
• 分子量: 445.53300
• 闪点: 329.3ºC
• 精确质量: 445.14600
• PSA: 78.43000
• LogP: 4.64690
• 折射率: 1.679
• 储存条件: 库房通风低温干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UR0809230 CHEMICAL NAME : 2H-Pyrazolo(4,3-c)quinoline, 3,3a,4,5-tetrahydro-2-acetyl-5-((4-methylphenyl)sulfo nyl)- 3-phenyl-, cis- CAS REGISTRY NUMBER : 76298-68-5 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C25-H23-N3-O3-S MOLECULAR WEIGHT : 445.57 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 800 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including Medicinal Chemistry. (Publications & Information Directorate, Council of Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012, India) V.14B- 1976- Volume(issue)/page/year: 19,297,1980 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 100 mg/kg SEX/DURATION : female 1-5 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) REFERENCE : IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including Medicinal Chemistry. (Publications & Information Directorate, Council of Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012, India) V.14B- 1976- Volume(issue)/page/year: 19,297,1980

合成路线

62750-11-2 ~% 76298-68-5

文献：Kelkar, Prabhakar M.; Sangwan, Naresh K.; Rastogi, Shri Nivas; Anand, Nitya Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 4 p. 297 - 300

14278-37-6 ~% 76298-68-5

文献：Kelkar, Prabhakar M.; Sangwan, Naresh K.; Rastogi, Shri Nivas; Anand, Nitya Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 4 p. 297 - 300

65148-06-3 ~% 76298-68-5

文献：Kelkar, Prabhakar M.; Sangwan, Naresh K.; Rastogi, Shri Nivas; Anand, Nitya Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 4 p. 297 - 300

74497-02-2 ~% 76298-68-5

文献：Kelkar, Prabhakar M.; Sangwan, Naresh K.; Rastogi, Shri Nivas; Anand, Nitya Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 4 p. 297 - 300