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26195-68-6

26195-68-6结构式

常用中文名：Acetamide,2-fluoro-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-,(S)- (9CI)
常用英文名：Acetamide,2-fluoro-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-,(S)- (9CI)
CAS号：26195-68-6
分子式：C₂₂H₂₄FNO₆
分子量：417.42700
发布时间：2017-11-23 11:03:28
更新时间：2023-01-16 15:27:37

化源商城直购

英文名	2-fluoro-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
英文别名	Acetamide,2-fluoro-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl) COLCHICINE,17-FLUORO 17-Fluorocolchicine Fluorocolchicine

密度	1.29g/cm3
沸点	733.2ºC at 760mmHg
分子式	C₂₂H₂₄FNO₆
分子量	417.42700
闪点	397.2ºC
精确质量	417.15900
PSA	83.09000
LogP	3.21210
蒸汽压	2.34E-21mmHg at 25°C
折射率	1.574

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GH0887000

CHEMICAL NAME :: Colchicine, 17-fluoro-

CAS REGISTRY NUMBER :: 26195-68-6

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C22-H24-F-N-O6

MOLECULAR WEIGHT :: 417.47

WISWESSER LINE NOTATION :: L B677 MV&T&J CO1 DO1 EO1 JMV1F NO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 852 ug/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,636,1981