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38479-08-2

38479-08-2结构式
38479-08-2结构式

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英文名 Acetamide, 2-chloro-N-[5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenz[a]heptalen-7-yl]-, (S)
英文别名 17-Chloro-10-demethoxy-10-methylthiocolchicine
密度 1.33g/cm3
沸点 749.2ºC at 760 mmHg
分子式 C22H24ClNO5S
分子量 449.94800
闪点 406.9ºC
精确质量 449.10600
PSA 99.16000
LogP 4.19470
折射率 1.615

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB5839000
CHEMICAL NAME :
Acetamide, 2-chloro-N-(5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(m ethylthio)-9-oxobenzo (a) heptalen-7-yl)-, (S)-
CAS REGISTRY NUMBER :
38479-08-2
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C22-H24-Cl-N-O5-S
MOLECULAR WEIGHT :
449.98
WISWESSER LINE NOTATION :
L B677 MV&T&J CO1 DO1 EO1 JMV1G NS1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1007 ug/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,636,1981