84332-25-2

• 常用中文名：5-Pyrimidinecarboxamide, N-((1-benzyl-2-pyrrolidinyl)methyl)-4-methoxy-2-(methylamino)-, dihydrochloride
• 常用英文名：5-Pyrimidinecarboxamide, N-((1-benzyl-2-pyrrolidinyl)methyl)-4-methoxy-2-(methylamino)-, dihydrochloride
• CAS号：84332-25-2
• 分子式：C₁₉H₂₇Cl₂N₅O₂
• 分子量：428.35600
• 发布时间：2016-03-15 09:34:29
• 更新时间：2024-01-09 20:50:13

名称

• 英文名: N-[(1-benzylpyrrolidin-2-yl)methyl]-4-methoxy-2-(methylamino)pyrimidine-5-carboxamide,dihydrochloride
• 英文别名: N-[(1-benzylpyrrolidin-2-yl)methyl]-4-methoxy-2-(methylamino)pyrimidine-5-carboxamide dihydrochloride; 5-Pyrimidinecarboxamide,N-((1-benzyl-2-pyrrolidinyl)methyl)-4-methoxy-2-(methylamino)-,dihydrochloride

物化性质

• 沸点: 607.6ºC at 760 mmHg
• 分子式: C₁₉H₂₇Cl₂N₅O₂
• 分子量: 428.35600
• 闪点: 321.3ºC
• 精确质量: 427.15400
• PSA: 86.10000
• LogP: 3.45990

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UV7707600 CHEMICAL NAME : 5-Pyrimidinecarboxamide, N-((1-benzyl-2-pyrrolidinyl)methyl)-4-methoxy-2-(meth ylamino)-, dihydrochloride CAS REGISTRY NUMBER : 84332-25-2 LAST UPDATED : 198609 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C19-H25-N5-O2.2Cl-H MOLECULAR WEIGHT : 428.41 WISWESSER LINE NOTATION : T6N CNJ BM1 DO1 EVM1- BT5NTJ A1R &GH 2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 105 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 17,437,1982

合成路线

72419-31-9 ~% 84332-25-2

文献：Dostert; Imbert; Ancher; et al. European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444

72419-45-5 ~% 84332-25-2

文献：Dostert; Imbert; Ancher; et al. European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444

84331-97-5 ~% 84332-25-2

文献：Dostert; Imbert; Ancher; et al. European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444

53554-29-3 ~% 84332-25-2

文献：Dostert; Imbert; Ancher; et al. European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444

57734-44-8 72418-39-4 ~% 84332-25-2

文献：Dostert; Imbert; Ancher; et al. European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444