864291-95-2

• 常用中文名：4-fluoro-1-piperidin-4-ylpiperidine,dihydrochloride
• 常用英文名：4-fluoro-1-piperidin-4-ylpiperidine,dihydrochloride
• CAS号：864291-95-2
• 分子式：C₁₀H₂₁Cl₂FN₂
• 分子量：259.19200
• 发布时间：2017-02-23 08:09:10
• 更新时间：2024-01-10 18:42:02

名称

• 英文名: 4-fluoro-1-piperidin-4-ylpiperidine,dihydrochloride
• 英文别名: 4-FLUORO-1,4'-BIPIPERIDINE DIHYDROCHLORIDE; 4-fluoro-1,4'-bipiperidine

物化性质

• 分子式: C₁₀H₂₁Cl₂FN₂
• 分子量: 259.19200
• 精确质量: 258.10700
• PSA: 15.27000
• LogP: 3.04300

合成路线

1335116-37-4 ~93% 864291-95-2

文献：GLAXOSMITHKLINE LLC; BROOKS, Carl, A.; CHEUNG, Mui; EIDAM, Hilary, S.; FOX, Ryan, M.; HILFIKER, Mark, A.; MANAS, Eric, S.; YE, Guosen Patent: WO2011/119701 A1, 2011 ; Location in patent: Page/Page column 38-39 ; WO 2011/119701 A1

864293-20-9 ~% 864291-95-2

文献：Yokoyama, Kazuhiro; Ishikawa, Noriko; Igarashi, Susumu; Kawano, Noriyuki; Hattori, Kazuyuki; Miyazaki, Takahiro; Ogino, Shin-ichi; Matsumoto, Yuzo; Takeuchi, Makoto; Ohta, Mitsuaki Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 14 p. 7021 - 7032

367500-88-7 ~% 864291-95-2

文献：GLAXOSMITHKLINE LLC; BROOKS, Carl, A.; CHEUNG, Mui; EIDAM, Hilary, S.; FOX, Ryan, M.; HILFIKER, Mark, A.; MANAS, Eric, S.; YE, Guosen Patent: WO2011/119701 A1, 2011 ; WO 2011/119701 A1

5382-16-1 ~% 864291-95-2

文献：GLAXOSMITHKLINE LLC; BROOKS, Carl, A.; CHEUNG, Mui; EIDAM, Hilary, S.; FOX, Ryan, M.; HILFIKER, Mark, A.; MANAS, Eric, S.; YE, Guosen Patent: WO2011/119701 A1, 2011 ; WO 2011/119701 A1

79099-07-3 ~% 864291-95-2

文献：GLAXOSMITHKLINE LLC; BROOKS, Carl, A.; CHEUNG, Mui; EIDAM, Hilary, S.; FOX, Ryan, M.; HILFIKER, Mark, A.; MANAS, Eric, S.; YE, Guosen Patent: WO2011/119701 A1, 2011 ; WO 2011/119701 A1