83278-86-8

• 常用中文名：2-羟甲基苯并二氢吡喃
• 常用英文名：3,4-Dihydro-2H-chromen-2-yl methanol
• CAS号：83278-86-8
• 分子式：C₁₀H₁₂O₂
• 分子量：164.20100
• 发布时间：2018-04-28 08:00:00
• 更新时间：2024-01-09 21:05:04

名称

• 中文名: 2-羟甲基苯并二氢吡喃
• 英文名: 3,4-dihydro-2h-chromen-2-ylmethanol
• 中文别名: 3,4-二氢-2H-苯并吡喃-2-甲醇
• 英文别名: 2-chromanemethanol; 2-hydroxy-methylchroman; 2-HYDROXYMETHYLCHROMANE; 2R-(hydroxymethyl)-chroman; hydroxymethyl-2 chromanne; (3,4-Dihydro-2H-chromen-2-yl)methanol,(3,4-Dihydro-2H-1-benzopyran-2-yl)methanol; (chroman-2-yl)methanol; 3,4-dihydro-2H-1-benzopyran-2-methanol; 3,4-dihydro-2H-1-benzopyran-2-ylMethanol

物化性质

• 密度: 1.125 g/cm3
• 沸点: 293.2ºC at 760 mmHg
• 熔点: 44 °C
• 分子式: C₁₀H₁₂O₂
• 分子量: 164.20100
• 闪点: 133.9ºC
• 精确质量: 164.08400
• PSA: 29.46000
• LogP: 1.37250
• 储存条件: 室温， 避光保存， 惰性气氛

MSDS

Name: 3 4-Dihydro-2H-chromen-2-ylmethanol Material Safety Data Sheet Synonym: CAS: 83278-86-8 Section 1 - Chemical Product MSDS Name:3 4-Dihydro-2H-chromen-2-ylmethanol Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 83278-86-8 3,4-Dihydro-2H-chromen-2-ylmethanol 97+% unlisted Hazard Symbols: XN Risk Phrases: 21/22 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. Harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: Causes respiratory tract irritation. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 83278-86-8: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: Colourless Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C10H12O2 Molecular Weight: 164.21 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents, strong bases, halogens, halogenated agents. Hazardous Decomposition Products: Carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 83278-86-8 unlisted. LD50/LC50: Not available. Carcinogenicity: 3,4-Dihydro-2H-chromen-2-ylmethanol - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 21/22 Harmful in contact with skin and if swallowed. R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 23 Do not inhale gas/fumes/vapour/spray. S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 83278-86-8: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 83278-86-8 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 83278-86-8 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 海关编码: 2932999099

合成路线

51939-71-0 ~89% 83278-86-8

文献：Payard; Mouysset; Tronche; Bastide European Journal of Medicinal Chemistry, 1985 , vol. 20, # 2 p. 117 - 120

24698-77-9 ~94% 83278-86-8

文献：Laboratorios Menarini S.A. Patent: US5990142 A1, 1999 ;

59363-19-8 ~68% 83278-86-8

文献：Palucki, Michael; Yasuda, Nobuyoshi Tetrahedron Letters, 2005 , vol. 46, # 6 p. 987 - 990

66598-81-0 ~% 83278-86-8

文献：US4957928 A1, ;

83780-47-6 ~% 137590-29-5 83278-86-8

文献：US5326771 A1, ; US 5326771 A

694-80-4 ~% 83278-86-8

文献：Tetrahedron Letters, , vol. 46, # 6 p. 987 - 990

上下游产品

上游产品  6
51939-71-0 24698-77-9 59363-19-8 66598-81-0
83780-47-6 694-80-4
下游产品  1
40515-95-5

海关

海关编码	2932999099
中文概述	2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%