CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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UY8350000
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CHEMICAL NAME :
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1H-Pyrrolizine-7-methanol, 2,3-dihydro-1-hydroxy-, (S)-
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CAS REGISTRY NUMBER :
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26400-24-8
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LAST UPDATED :
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199012
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DATA ITEMS CITED :
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11
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MOLECULAR FORMULA :
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C8-H11-N-O2
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MOLECULAR WEIGHT :
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153.20
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WISWESSER LINE NOTATION :
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T55 AN&TJ D1Q FQ -S
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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92 mg/kg
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TOXIC EFFECTS :
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Liver - other changes
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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DOSE :
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40 mg/kg
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SEX/DURATION :
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female 14 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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DOSE :
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60 mg/kg
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SEX/DURATION :
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female 14 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Effects on Embryo or Fetus - fetal death
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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DOSE :
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30 mg/kg
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SEX/DURATION :
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female 14 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord)
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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DOSE :
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40 mg/kg
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SEX/DURATION :
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female 14 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
MUTATION DATA
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TYPE OF TEST :
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Cytogenetic analysis
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TEST SYSTEM :
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Mammal - species unspecified Leukocyte
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DOSE/DURATION :
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500 nmol/L
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REFERENCE :
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CYTBAI Cytobios. (Faculty Press, 88 Regent St., Cambridge, UK) V.1- 1969- Volume(issue)/page/year: 3,245,1971
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