161373-46-2

• 常用中文名：4-氨基-6-氨基-3-羧酸
• 常用英文名：4-amino-6-chlorocinnoline-3-carboxylic acid
• CAS号：161373-46-2
• 分子式：C₉H₆ClN₃O₂
• 分子量：223.61600
• 发布时间：2016-03-31 11:33:27
• 更新时间：2024-03-05 18:28:55

名称

• 中文名: 4-氨基-6-氨基-3-羧酸
• 英文名: 4-amino-6-chlorocinnoline-3-carboxylic acid
• 英文别名: 3-Cinnolinecarboxylicacid,4-amino-6-chloro; 4-Amino-6-chloro-3-cinnolinecarboxylic acid hydrate; 3-Cinnolinecarboxylic acid,4-amino-6-chloro-,hydrate

物化性质

• 密度: 1.635g/cm3
• 沸点: 459.1ºC at 760mmHg
• 分子式: C₉H₆ClN₃O₂
• 分子量: 223.61600
• 闪点: 231.4ºC
• 精确质量: 223.01500
• PSA: 89.10000
• LogP: 2.14480
• 蒸汽压: 3.2E-09mmHg at 25°C
• 折射率: 1.761
• 储存条件: 室温

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : GE3623682 CHEMICAL NAME : 3-Cinnolinecarboxylic acid, 4-amino-6-chloro-, hydrate CAS REGISTRY NUMBER : 161373-46-2 LAST UPDATED : 199603 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C9-H6-Cl-N3-O2.H2-O MOLECULAR WEIGHT : 241.65 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 1200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 49,884,1994 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 600 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 49,884,1994

合成路线

161373-33-7 ~78% 161373-46-2

文献：Stanczak; Kwapiszewski; Lewgowd; Ochocki; Szadowska; Pakulska; Glowka Pharmazie, 1994 , vol. 49, # 12 p. 884 - 889

106-47-8 ~% 161373-46-2

文献：Stanczak; Kwapiszewski; Lewgowd; Ochocki; Szadowska; Pakulska; Glowka Pharmazie, 1994 , vol. 49, # 12 p. 884 - 889

20931-91-3 ~% 161373-46-2

文献：Stanczak; Kwapiszewski; Lewgowd; Ochocki; Szadowska; Pakulska; Glowka Pharmazie, 1994 , vol. 49, # 12 p. 884 - 889