928853-86-5

• 常用中文名：15-Lipoxygenase Inhibitor 1
• 常用英文名：4-MMPB
• CAS号：928853-86-5
• 分子式：C₁₆H₁₉N₅S
• 分子量：313.421
• 发布时间：2016-04-19 02:06:33
• 更新时间：2024-01-08 17:27:33
• 5-Lipoxygenases (15-LO) inhibitor 1 is a heterocyclic pyrimidobenzothiazine compound that inhibits 15-LO with an IC50 value of 18 µM.

名称

• 中文名: 15-Lipoxygenase Inhibitor 1
• 英文名: 4-methyl-2-(4-methylpiperazin-1-yl)-5H-pyrimido[4,5-b][1,4]benzothiazine
• 英文别名: 4-methyl-2-(4-methylpiperazin-1-yl)-5H-pyrimido[4,5-b][1,4]benzothiazine; 5H-Pyrimido[4,5-b][1,4]benzothiazine, 4-methyl-2-(4-methyl-1-piperazinyl)-; 4-Methyl-2-(4-methyl-1-piperazinyl)-5H-pyrimido[4,5-b][1,4]benzothiazine; 4-MMPB

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 532.1±60.0 °C at 760 mmHg
• 分子式: C₁₆H₁₉N₅S
• 分子量: 313.421
• 闪点: 275.6±32.9 °C
• 精确质量: 313.136108
• PSA: 69.59000
• LogP: 3.35
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.649
• 储存条件: -20°C，密闭，干燥

合成路线

928853-78-5 ~53% 928853-86-5

文献：Bakavoli; Nikpour; Rahimizadeh; Saberi; Sadeghian Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 5 p. 2120 - 2126

928853-74-1 ~% 928853-86-5

文献：Bakavoli; Nikpour; Rahimizadeh; Saberi; Sadeghian Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 5 p. 2120 - 2126

56745-01-8 ~% 928853-86-5

文献：Bakavoli; Nikpour; Rahimizadeh; Saberi; Sadeghian Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 5 p. 2120 - 2126

137-07-5 ~% 928853-86-5

文献：Bakavoli; Nikpour; Rahimizadeh; Saberi; Sadeghian Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 5 p. 2120 - 2126