83624-01-5

• 常用中文名：(2S,4R)-1-(叔丁氧羰基)-4-甲氧基吡咯烷-2-羧酸
• 常用英文名：(2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid
• CAS号：83624-01-5
• 分子式：C₁₁H₁₉NO₅
• 分子量：245.272
• 发布时间：2016-02-24 20:51:50
• 更新时间：2024-01-08 13:43:12

名称

• 中文名: (2S,4R)-1-(叔丁氧羰基)-4-甲氧基吡咯烷-2-羧酸
• 英文名: (2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid
• 英文别名: (4R)-4-Methoxy-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-proline; (2S,4R)-4-methoxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid; 1,2-Pyrrolidinedicarboxylic acid, 4-methoxy-, 1-(1,1-dimethylethyl) ester, (2S,4R)-

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 362.0±42.0 °C at 760 mmHg
• 分子式: C₁₁H₁₉NO₅
• 分子量: 245.272
• 闪点: 172.7±27.9 °C
• 精确质量: 245.126328
• PSA: 76.07000
• LogP: -0.07
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.500
• 储存条件: 室温

合成路线

13726-69-7 74-88-4 ~65% 83624-01-5

文献：Bristol-Myers Squibb Company Patent: US2007/232679 A1, 2007 ; Location in patent: Page/Page column 11 ; US 20070232679 A1

24424-99-5 ~% 83624-01-5

文献：DAIICHI PHARMACEUTICAL CO., LTD. Patent: EP1757602 A1, 2007 ;

426844-31-7 ~99% 83624-01-5

文献：Chiba, Jun; Takayama, Gensuke; Takashi, Tohru; Yokoyama, Mika; Nakayama, Atsushi; Baldwin, John J.; McDonald, Edward; Moriarty, Kevin J.; Sarko, Christopher R.; Saionz, Kurt W.; Swanson, Robert; Hussain, Zahid; Wong, Angela; MacHinaga, Nobuo Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 8 p. 2725 - 2746

74844-91-0 ~% 83624-01-5

文献：Chiba, Jun; Takayama, Gensuke; Takashi, Tohru; Yokoyama, Mika; Nakayama, Atsushi; Baldwin, John J.; McDonald, Edward; Moriarty, Kevin J.; Sarko, Christopher R.; Saionz, Kurt W.; Swanson, Robert; Hussain, Zahid; Wong, Angela; MacHinaga, Nobuo Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 8 p. 2725 - 2746

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