10077-96-0

• 常用中文名：4-氨基安替比林N-氨基甲酸甲酯
• 常用英文名：4-Aminoantipyrine N-Carbamic Acid Methyl Ester
• CAS号：10077-96-0
• 分子式：C₁₃H₁₅N₃O₃
• 分子量：261.27600
• 发布时间：2017-05-11 10:33:22
• 更新时间：2024-01-13 13:23:44

名称

• 中文名: 4-氨基安替比林N-氨基甲酸甲酯
• 英文名: methyl N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)carbamate
• 英文别名: 2,3-Dimethyl-5-oxo-3-pyrazoline-4-carbamic acid methyl ester; 2,3-dimethyl-5-oxo-1-phenyl-3-pyrazoline-4-carbamic acid methyl ester; F0300-0167; 3-Pyrazoline-4-carbamic acid,2,3-dimethyl-5-oxo-,methyl ester; 4-Aminoantipyrine N-Carbamic Acid Methyl Ester; 4-Methoxycarbonylamino-2,3-dimethyl-1-phenyl-pyrazol-5-on; 4-Carbomethoxyamino-2,3-dimethyl-1-phenylpyrazol-5-one

物化性质

• 密度: 1.3g/cm3
• 分子式: C₁₃H₁₅N₃O₃
• 分子量: 261.27600
• 精确质量: 261.11100
• PSA: 68.75000
• LogP: 1.67630
• 折射率: 1.615

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UQ8955000 CHEMICAL NAME : 3-Pyrazoline-4-carbamic acid, 2,3-dimethyl-5-oxo-, methyl ester CAS REGISTRY NUMBER : 10077-96-0 BEILSTEIN REFERENCE NO. : 0276625 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C13-H15-N3-O3 MOLECULAR WEIGHT : 261.31 WISWESSER LINE NOTATION : T5NNVJ A1 BR& DMVO1 E1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 58 mg/kg TOXIC EFFECTS : Nutritional and Gross Metabolic - body temperature decrease Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 15,396,1981

合成路线

83-07-8 616-38-6 ~84% 10077-96-0

文献：Lissel, Manfred; Rohani-Dezfuli, Ali Reza; Vogt, Gabriele Journal of Chemical Research, Miniprint, 1989 , # 10 p. 2434 - 2452

83-07-8 79-22-1 ~95% 10077-96-0

文献：Voronon, V. G.; Shramova, Z. I.; Aleshina, V. A.; Zaks, A. S.; Pidemskii, E. L.; Goleneva, A. F. Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 6 p. 396 - 399 Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 6 p. 35 - 39

100374-19-4 ~% 10077-96-0

文献：Yakugaku Zasshi, , vol. 79, p. 172,175 Chem.Abstr., , p. 13138

上下游产品

上游产品  4
83-07-8 616-38-6 79-22-1 100374-19-4
下游产品  1
10116-07-1