20013-22-3

• 常用中文名：N-甲基金雀花碱氢碘酸盐
• 常用英文名：Caulophylline hydriodide
• CAS号：20013-22-3
• 分子式：C₁₂H₁₇IN₂O
• 分子量：332.181
• 发布时间：2018-08-19 12:06:16
• 更新时间：2024-01-11 14:02:38

名称

• 中文名: N-甲基金雀花碱氢碘酸盐
• 英文名: Caulophylline hydriodide
• 英文别名: (1R)-3-methyl-1,2,3,4,5,6-hexahydro-1r,5c-methano-pyrido[1,2-a][1,5]diazocin-8-one,hydriodide; (1R)-3-Methyl-1,2,3,4,5,6-hexahydro-1r,5c-methano-pyrido[1,2-a][1,5]diazocin-8-on,Hydroiodid; N-Methylcytisine hydriodide; C12H17N2O.I; N-methylcytisine,monohydroiodide,(1R-cis)-isomer; CYTISINE,12-METHYL-,HYDROGEN IODIDE; Caulophylline,monohydriodide (8CI); 1,5-Methano-2H-pyrido[1,2-a][1,5]diazocinium, 1,3,4,5,6,8-hexahydro-12-methyl-8-oxo-, iodide (1:1); Caulophyllinehydriodide; Caulophylline,monohydriodide; (-)-7R:9S-Caulophylline hydrogen iodide; 13-Methyl-6-oxo-11-aza-7-azoniatricyclo[7.3.1.0]trideca-2,4-diene iodide

物化性质

• 沸点: 408.9ºC at 760 mmHg
• 分子式: C₁₂H₁₇IN₂O
• 分子量: 332.181
• 闪点: 201.1ºC
• 精确质量: 332.038544
• PSA: 34.03000
• LogP: 2.12800
• 外观性状: 固体
• 蒸汽压: 6.75E-07mmHg at 25°C
• 储存条件: 2-8°C， 干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : HA4550000 CHEMICAL NAME : Cytisine, 12-methyl-, hydrogen iodide CAS REGISTRY NUMBER : 20013-22-3 LAST UPDATED : 199207 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C12-H16-N2-O.H-I MOLECULAR WEIGHT : 332.21 WISWESSER LINE NOTATION : T C666 A GVN LM&TTJ &IH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >830 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BJPCBM British Journal of Pharmacology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.34- 1968- Volume(issue)/page/year: 35,161,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 51 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy) REFERENCE : BJPCBM British Journal of Pharmacology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.34- 1968- Volume(issue)/page/year: 35,161,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 21 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy) REFERENCE : BJPCBM British Journal of Pharmacology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.34- 1968- Volume(issue)/page/year: 35,161,1969

安全

• 危害码 (欧洲): Xn