63867-52-7

• 常用中文名：2-[(4,5-diphenyl-1,3-oxazol-2-yl)-(2-hydroxyethyl)amino]ethanol,hydrate
• 常用英文名：2-[(4,5-diphenyl-1,3-oxazol-2-yl)-(2-hydroxyethyl)amino]ethanol,hydrate
• CAS号：63867-52-7
• 分子式：C₁₉H₂₂N₂O₄
• 分子量：342.38900
• 发布时间：2017-12-21 05:11:17
• 更新时间：2023-01-17 18:18:49

名称

• 英文名: 2-[(4,5-diphenyl-1,3-oxazol-2-yl)-(2-hydroxyethyl)amino]ethanol,hydrate
• 英文别名: S 222; Diethamphenazol monohydrate; Ageroplas; Ditazol monohydrate

物化性质

• 沸点: 505.5ºC at 760 mmHg
• 分子式: C₁₉H₂₂N₂O₄
• 分子量: 342.38900
• 闪点: 259.5ºC
• 精确质量: 342.15800
• PSA: 78.96000
• LogP: 2.73530

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KK7400000 CHEMICAL NAME : Ethanol, 2,2'-((4,5-diphenyl-2-oxazolyl)imino)di-, monohydrate CAS REGISTRY NUMBER : 63867-52-7 LAST UPDATED : 199007 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C19-H20-N2-O3.H2-O MOLECULAR WEIGHT : 342.43 WISWESSER LINE NOTATION : T5N COJ BN2Q2Q DR& ER &QH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 11380 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,1283,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 7770 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,1283,1973 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2300 mg/kg TOXIC EFFECTS : Behavioral - analgesia Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,1092,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3390 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,1283,1973