345629-23-4

• 常用中文名：tert-butyl 4-((5-((5-tert-butyloxazol-2-yl) Methylthio)thiazol-2-yl)carbamoyl)piperidine-1-carboxylate
• 常用英文名：tert-butyl 4-((5-((5-tert-butyloxazol-2-yl) Methylthio)thiazol-2-yl)carbamoyl)piperidine-1-carboxylate
• CAS号：345629-23-4
• 分子式：C₂₂H₃₂N₄O₄S₂
• 分子量：480.64400
• 发布时间：2016-02-10 10:40:51
• 更新时间：2024-01-10 13:58:17

名称

• 英文名: 2-Methyl-2-propanyl 4-{[5-({[5-(2-methyl-2-propanyl)-1,3-oxazol-2 -yl]methyl}sulfanyl)-1,3-thiazol-2-yl]carbamoyl}-1-piperidinecarb oxylate
• 英文别名: tert-butyl 4-oxo-1,4'-bipiperidine-1'-carboxylate

物化性质

• 分子式: C₂₂H₃₂N₄O₄S₂
• 分子量: 480.64400
• 精确质量: 480.18600
• PSA: 154.59000
• LogP: 5.89390

合成路线

84358-13-4 224436-97-9 ~76% 345629-23-4

文献：Misra, Raj N.; Xiao, Hai-Yun; Kim, Kyoung S.; Lu, Songfeng; Han, Wen-Ching; Barbosa, Stephanie A.; Hunt, John T.; Rawlins, David B.; Shan, Weifang; Ahmed, Syed Z.; Qian, Ligang; Chen, Bang-Chi; Zhao, Rulin; Bednarz, Mark S.; Kellar, Kristen A.; Mulheron, Janet G.; Batorsky, Roberta; Roongta, Urvashi; Kamath, Amrita; Marathe, Punit; Ranadive, Sunanda A.; Sack, John S.; Tokarski, John S.; Pavletich, Nikola P.; Lee, Francis Y. F.; Webster, Kevin R.; Kimball, S. David Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1719 - 1728

76779-98-1 ~% 345629-23-4

文献：CURIS, INC. Patent: WO2009/36016 A1, 2009 ;

5469-26-1 ~% 345629-23-4

文献：Misra, Raj N.; Xiao, Hai-Yun; Kim, Kyoung S.; Lu, Songfeng; Han, Wen-Ching; Barbosa, Stephanie A.; Hunt, John T.; Rawlins, David B.; Shan, Weifang; Ahmed, Syed Z.; Qian, Ligang; Chen, Bang-Chi; Zhao, Rulin; Bednarz, Mark S.; Kellar, Kristen A.; Mulheron, Janet G.; Batorsky, Roberta; Roongta, Urvashi; Kamath, Amrita; Marathe, Punit; Ranadive, Sunanda A.; Sack, John S.; Tokarski, John S.; Pavletich, Nikola P.; Lee, Francis Y. F.; Webster, Kevin R.; Kimball, S. David Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1719 - 1728

224441-73-0 ~% 345629-23-4

文献：CURIS, INC. Patent: WO2009/36016 A1, 2009 ;

333389-44-9 ~% 345629-23-4

文献：CURIS, INC. Patent: WO2009/36016 A1, 2009 ;

498-94-2 ~% 345629-23-4

文献：Misra, Raj N.; Xiao, Hai-Yun; Kim, Kyoung S.; Lu, Songfeng; Han, Wen-Ching; Barbosa, Stephanie A.; Hunt, John T.; Rawlins, David B.; Shan, Weifang; Ahmed, Syed Z.; Qian, Ligang; Chen, Bang-Chi; Zhao, Rulin; Bednarz, Mark S.; Kellar, Kristen A.; Mulheron, Janet G.; Batorsky, Roberta; Roongta, Urvashi; Kamath, Amrita; Marathe, Punit; Ranadive, Sunanda A.; Sack, John S.; Tokarski, John S.; Pavletich, Nikola P.; Lee, Francis Y. F.; Webster, Kevin R.; Kimball, S. David Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1719 - 1728

24424-99-5 ~% 345629-23-4

文献：Misra, Raj N.; Xiao, Hai-Yun; Kim, Kyoung S.; Lu, Songfeng; Han, Wen-Ching; Barbosa, Stephanie A.; Hunt, John T.; Rawlins, David B.; Shan, Weifang; Ahmed, Syed Z.; Qian, Ligang; Chen, Bang-Chi; Zhao, Rulin; Bednarz, Mark S.; Kellar, Kristen A.; Mulheron, Janet G.; Batorsky, Roberta; Roongta, Urvashi; Kamath, Amrita; Marathe, Punit; Ranadive, Sunanda A.; Sack, John S.; Tokarski, John S.; Pavletich, Nikola P.; Lee, Francis Y. F.; Webster, Kevin R.; Kimball, S. David Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1719 - 1728

13547-70-1 ~% 345629-23-4

文献：CURIS, INC. Patent: WO2009/36016 A1, 2009 ;

上下游产品

上游产品  9
84358-13-4 224436-97-9 76779-98-1 5469-26-1
224441-73-0 333389-44-9 498-94-2 24424-99-5
13547-70-1
下游产品  1
345627-80-7