167479-78-9

• 常用中文名：(S)-2-氨基-3-(4-氰基苯基)丙酸
• 常用英文名：4-Cyanophenylalanine
• CAS号：167479-78-9
• 分子式：C₁₀H₁₀N₂O₂
• 分子量：190.199
• 相关类别： 生物化工 氨基酸及其衍生物 苯丙氨酸类衍生物
• 发布时间：2018-05-11 08:00:00
• 更新时间：2024-01-02 10:52:35

名称

• 中文名: L-4-氰基苯丙氨酸
• 英文名: (S)-2-Amino-3-(4-cyanophenyl)propanoic acid
• 中文别名: L-对氰基苯丙氨酸
• 英文别名: (L)-4-Cyanophenylalanine; 4-Cyanophenylalanine; (S)-2-Amino-3-(4-cyanophenyl)propanoic acid; para-Cyano-L-phenylalanine; Phenylalanine, 4-cyano-; p-cyano-phenylalanine; (2S)-2-amino-3-(4-cyanophenyl)propanoic acid; L-4-Cyanophenylalanine; MFCD00270363

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 394.1±37.0 °C at 760 mmHg
• 熔点: -243ºC
• 分子式: C₁₀H₁₀N₂O₂
• 分子量: 190.199
• 闪点: 192.1±26.5 °C
• 精确质量: 190.074234
• PSA: 87.11000
• LogP: 0.55
• 外观性状: 白色粉末
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.596
• 储存条件: -15°C

MSDS

Material Safety Data Sheet Section1. Identification of the substance Product Name: L-(S)-4-Cyanophenylalanine Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled P261:Avoid breathing dust/fume/gas/mist/vapours/spray P280:Wear protective gloves/protective clothing/eye protection/face protection P304+P340:IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing P301+P312:IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell P312:Call a POISON CENTER or doctor/physician if you feel unwell Section3. Composition/information on ingredients. Ingredient name:L-(S)-4-Cyanophenylalanine CAS number:167479-78-9 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Storage:Store in closed vessels. Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Not specified Appearance: Boiling point:No data Melting point:No data Flash point:No data Density:No data Molecular formula:C10H10N2O2 Molecular weight:190.2 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information UN Number:UN3439 Class: 6.1 Packing group: III Proper shipping name: NITRILES, TOXIC, SOLID, N.O.S. (L-(S)-4-Cyanophenylalanine) Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi
• 海关编码: 2926909090

合成路线

146664-08-6 ~70% 167479-78-9

文献：Pearson, Daniel A.; Lister-James, John; McBride, William J.; Wilson, David M.; Martel, Lawrence J.; Civitello, Edgar R.; Dean, Richard T. Journal of Medicinal Chemistry, 1996 , vol. 39, # 7 p. 1372 - 1382

17201-43-3 ~% 167479-78-9

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 17 p. 2483 - 2486

104-85-8 ~% 167479-78-9

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 17 p. 2483 - 2486

52117-01-8 ~% 167479-78-9

文献：Journal of Medicinal Chemistry, , vol. 39, # 7 p. 1372 - 1382

上下游产品

上游产品  3
146664-08-6 17201-43-3 104-85-8
下游产品  2
131724-45-3 173963-93-4

海关

海关编码	2926909090
中文概述	2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%