121524-18-3

• 常用中文名：(E)-1-[(2R)-2-(2-hydroxyethyl)piperidin-1-yl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)prop-2-en-1-one
• 常用英文名：(E)-1-[(2R)-2-(2-hydroxyethyl)piperidin-1-yl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)prop-2-en-1-one
• CAS号：121524-18-3
• 分子式：C₂₃H₂₅N₃O₂
• 分子量：375.46400
• 发布时间：2016-07-19 20:28:21
• 更新时间：2024-02-01 12:31:27

名称

• 英文名: (E)-1-[(2R)-2-(2-hydroxyethyl)piperidin-1-yl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)prop-2-en-1-one
• 英文别名: 2-Piperidineethanol,1-(1-oxo-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-2-propenyl)-,(R-(E)); C23H25N3O2; (R-(E))-1-(1-Oxo-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-2-propenyl)-2-piperidineethanol; FK 453; (+)-(R)-((E)-3-(2-Phenylpyrazolo(1,5-a)pyridin-3-yl)acryloyl)-2-piperidineethanol

物化性质

• 密度: 1.21g/cm3
• 分子式: C₂₃H₂₅N₃O₂
• 分子量: 375.46400
• 精确质量: 375.19500
• PSA: 57.84000
• LogP: 3.71590
• 折射率: 1.636

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TM9475500 CHEMICAL NAME : 2-Piperidineethanol, 1-(1-oxo-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-2-pr openyl)-, (R-(E))- CAS REGISTRY NUMBER : 121524-18-3 LAST UPDATED : 199606 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C23-H25-N3-O2 MOLECULAR WEIGHT : 375.51 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 46,185,1996