135718-67-1

• 常用中文名：3-Amino-4-phenyl-2-methylmercapto-3,4,5,6,7,8-hexahydrobenzo(4,5)thien o(2,3-d)pyrimidine HI
• 常用英文名：3-Amino-4-phenyl-2-methylmercapto-3,4,5,6,7,8-hexahydrobenzo(4,5)thien o(2,3-d)pyrimidine HI
• CAS号：135718-67-1
• 分子式：C₁₇H₂₀IN₃S₂
• 分子量：457.39500
• 发布时间：2016-06-14 03:12:46
• 更新时间：2024-04-05 17:30:44

名称

• 英文名: 2-methylsulfanyl-4-phenyl-5,6,7,8-tetrahydro-4H-[1]benzothiolo[2,3-d]pyrimidin-3-amine,hydroiodide
• 英文别名: (1)Benzothieno(2,3-d)pyrimidin-3(4H)-amine,5,6,7,8-tetrahydro-2-(methylthio)-4-phenyl-,monohydriodide; 3-amino-4-phenyl-2-methylmercapto-3,4,5,6,7,8-hexahydrobenzo<4,5>thieno<2,3-d>pyrimidine hydroiodide; 2-methylsulfanyl-4-phenyl-5,6,7,8-tetrahydro-4H-[1]benzothiolo[2,3-d]pyrimidin-3-amine hydroiodide; 3-Amino-4-phenyl-2-methylmercapto-3,4,5,6,7,8-hexahydrobenzo(4,5)thieno(2,3-d)pyrimidine HI

物化性质

• 沸点: 524ºC at 760mmHg
• 分子式: C₁₇H₂₀IN₃S₂
• 分子量: 457.39500
• 闪点: 270.7ºC
• 精确质量: 457.01400
• PSA: 95.16000
• LogP: 5.32810
• 蒸汽压: 4.5E-11mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DL8240000 CHEMICAL NAME : (1)Benzothieno(2,3-d)pyrimidin-3(4H)-amine, 5,6,7,8-tetrahydro-2-(methylthio)-4-phenyl-, monohydriodide CAS REGISTRY NUMBER : 135718-67-1 LAST UPDATED : 199512 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C17-H19-N3-S2.H-I MOLECULAR WEIGHT : 457.42 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARPMAS Archiv der Pharmazie (Weinheim, Germany) (VCH Pub., Inc., 303 NW 12th Ave., Deerfield Beach, FL 33441) V.51-261, 1835-1923; V.305- 1972- Volume(issue)/page/year: 327,779,1994 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 26,323,1991

合成路线

128352-86-3 74-88-4 ~86% 135718-67-1

文献：Vega, S; Alonso, J; Diaz, JA; Junquera, F; Perez, C; et al. European Journal of Medicinal Chemistry, 1991 , vol. 26, # 3 p. 323 - 329

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