99734-97-1

• 常用中文名：1-Cyclopropyl-7-{3-[(ethylamino)methyl]-1-pyrrolidinyl}-6,8-diflu oro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
• 常用英文名：1-Cyclopropyl-7-{3-[(ethylamino)methyl]-1-pyrrolidinyl}-6,8-diflu oro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
• CAS号：99734-97-1
• 分子式：C₂₀H₂₃F₂N₃O₃
• 分子量：391.41200
• 发布时间：2017-03-30 10:23:25
• 更新时间：2024-01-29 16:57:06

名称

• 英文名: 1-Cyclopropyl-7-{3-[(ethylamino)methyl]-1-pyrrolidinyl}-6,8-diflu oro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
• 英文别名: 1-CYCLOPROPYL-7-(3-((ETHYLAMINO)METHYL)-1-PYRROLIDINYL)-6,8-DIFLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACID; Palladium,tris[tris(4-methylphenyl)phosphine]; Pd(P(p-tolyl)3)3; 1-cyclopropyl-7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; [Pd{P(p-tol)3}3]; tris(tri-p-tolylphosphine)palladium(0)

物化性质

• 密度: 1.397g/cm3
• 沸点: 567.8ºC at 760mmHg
• 分子式: C₂₀H₂₃F₂N₃O₃
• 分子量: 391.41200
• 闪点: 297.2ºC
• 精确质量: 391.17100
• PSA: 74.57000
• LogP: 3.20450

合成路线

94695-52-0 91187-83-6 ~85% 99734-97-1

文献：Sanchez, Joseph P.; Domagala, John M.; Hagen, Susan E.; Heifetz, Carl L.; Hutt, Marland P.; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, p. 983 - 991

103054-56-4 94242-51-0 91187-83-6 ~% 99734-97-1

文献：Warner-Lambert Company Patent: US4578473 A1, 1986 ;

94242-51-0 ~% 99734-97-1

文献：Domagala, John M.; Heifetz, Carl L.; Hutt, Marland P.; Mich, Thomas F.; Nichols, Jeffry B.; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, # 5 p. 991 - 1001

94695-50-8 ~% 99734-97-1

文献：Domagala, John M.; Heifetz, Carl L.; Hutt, Marland P.; Mich, Thomas F.; Nichols, Jeffry B.; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, # 5 p. 991 - 1001

94695-51-9 ~% 99734-97-1

文献：Domagala, John M.; Heifetz, Carl L.; Hutt, Marland P.; Mich, Thomas F.; Nichols, Jeffry B.; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, # 5 p. 991 - 1001

94695-48-4 ~% 99734-97-1

文献：Domagala, John M.; Heifetz, Carl L.; Hutt, Marland P.; Mich, Thomas F.; Nichols, Jeffry B.; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, # 5 p. 991 - 1001

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