CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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UV0361500
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CHEMICAL NAME :
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9H-Pyrido(3,4-b)indole, 1-methyl-7-pentyloxy-, hydrochloride
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CAS REGISTRY NUMBER :
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63885-68-7
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LAST UPDATED :
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199012
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C17-H20-N2-O.Cl-H
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MOLECULAR WEIGHT :
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304.85
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WISWESSER LINE NOTATION :
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T B656 EN HMJ F1 KO5 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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200 mg/kg
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TOXIC EFFECTS :
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Behavioral - tremor Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease
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REFERENCE :
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QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 5,56,1932
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - guinea pig
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DOSE/DURATION :
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400 mg/kg
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TOXIC EFFECTS :
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Behavioral - tremor Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease
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REFERENCE :
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QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 5,56,1932
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Amphibian - frog
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DOSE/DURATION :
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200 mg/kg
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TOXIC EFFECTS :
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Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - ataxia Nutritional and Gross Metabolic - body temperature increase
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REFERENCE :
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QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 5,56,1932
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