5606-59-7

• 常用中文名：7-chloro-N-methyl-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxamide
• 常用英文名：7-chloro-N-methyl-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxamide
• CAS号：5606-59-7
• 分子式：C₁₇H₁₄ClN₃O₂
• 分子量：327.76500
• 发布时间：2017-01-18 20:25:41
• 更新时间：2024-01-09 17:15:23

名称

• 英文名: 7-chloro-N-methyl-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxamide
• 英文别名: 7-Chloro-2,3-dihydro-N-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxamide; D-58M; 1H-1,4-Benzodiazepine-3-carboxamide,2,3-dihydro-7-chloro-N-methyl-2-oxo-5-phenyl; 1-Methylcarbamoyldiazepam

物化性质

• 分子式: C₁₇H₁₄ClN₃O₂
• 分子量: 327.76500
• 精确质量: 327.07700
• PSA: 77.54000
• LogP: 2.60510

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DE8747930 CHEMICAL NAME : 1H-1,4-Benzodiazepine-3-carboxamide, 2,3-dihydro-7-chloro-N-methyl-2-oxo-5-phenyl- CAS REGISTRY NUMBER : 5606-59-7 BEILSTEIN REFERENCE NO. : 0690746 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C17-H14-Cl-N3-O2 MOLECULAR WEIGHT : 327.79 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 840 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression REFERENCE : TAKHAA Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532, Japan) V.29- 1970- Volume(issue)/page/year: 29,134,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 460 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression REFERENCE : TAKHAA Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532, Japan) V.29- 1970- Volume(issue)/page/year: 29,134,1970