187231-58-9

• 常用中文名：(4-amino-7-fluorocinnolin-3-yl)-(4-pyridin-2-ylpiperazin-1-yl)methanone
• 常用英文名：(4-amino-7-fluorocinnolin-3-yl)-(4-pyridin-2-ylpiperazin-1-yl)methanone
• CAS号：187231-58-9
• 分子式：C₁₈H₁₇FN₆O
• 分子量：352.36600
• 发布时间：2016-01-20 09:17:41
• 更新时间：2025-09-17 19:11:38

名称

• 英文名: (4-amino-7-fluorocinnolin-3-yl)-(4-pyridin-2-ylpiperazin-1-yl)methanone

物化性质

• 密度: 1.409g/cm3
• 沸点: 638.7ºC at 760 mmHg
• 分子式: C₁₈H₁₇FN₆O
• 分子量: 352.36600
• 闪点: 340.1ºC
• 精确质量: 352.14500
• PSA: 88.24000
• LogP: 2.29260
• 蒸汽压: 3.26E-16mmHg at 25°C
• 折射率: 1.694

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TK8050833 CHEMICAL NAME : Piperazine, 1-((4-amino-7-fluoro-3-cinnolinyl)carbonyl)-4-(2-pyri dinyl)- CAS REGISTRY NUMBER : 187231-58-9 LAST UPDATED : 199803 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C18-H17-F-N6-O MOLECULAR WEIGHT : 352.41 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1750 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 52,91,1997 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 52,91,1997