77905-50-1

• 常用中文名：4-((Bis(2-chloroethyl)amino)methyl)-2-nitro-phenol hydrochloride
• 常用英文名：4-((Bis(2-chloroethyl)amino)methyl)-2-nitro-phenol hydrochloride
• CAS号：77905-50-1
• 分子式：C₁₁H₁₅Cl₃N₂O₃
• 分子量：329.60700
• 发布时间：2016-03-25 08:41:04
• 更新时间：2024-02-01 19:53:41

名称

• 英文名: 4-[bis(2-chloroethyl)aminomethyl]-2-nitrophenol,hydrochloride
• 英文别名: 4-[bis(2-chloroethyl)aminomethyl]-2-nitrophenol hydrochloride; 4-Hydroxy-3-nitrobenzyl-bis(2-chloroethyl)amine hydrochloride; Phenol,4-((bis(2-chloroethyl)amino)methyl)-2-nitro-,hydrochloride

物化性质

• 沸点: 339.9ºC at 760 mmHg
• 分子式: C₁₁H₁₅Cl₃N₂O₃
• 分子量: 329.60700
• 闪点: 159.4ºC
• 精确质量: 328.01500
• PSA: 69.29000
• LogP: 3.90520

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : SJ7781200 CHEMICAL NAME : Phenol, 4-((bis(2-chloroethyl)amino)methyl)-2-nitro-, hydrochloride CAS REGISTRY NUMBER : 77905-50-1 LAST UPDATED : 198609 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C11-H14-Cl2-N2-O3.Cl-H MOLECULAR WEIGHT : 329.63 WISWESSER LINE NOTATION : WNR BQ E1N2G2G &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 85 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Gastrointestinal - other changes REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 15,81,1981

合成路线

77905-44-3 ~66% 77905-50-1

文献：Stepanyan, G. M.; Margaryan, S. S.; Iradyan, M. A.; Garibdzhanyan, B. T. Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 2 p. 81 - 84 Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 2 p. 24 - 27