108461-05-8

• 常用中文名：1-cyclopropyl-6-fluoro-7-(8-methyl-3,8-diazabicyclo[3.2.1]octan-3-yl)-4-oxoquinoline-3-carboxylic acid
• 常用英文名：1-cyclopropyl-6-fluoro-7-(8-methyl-3,8-diazabicyclo[3.2.1]octan-3-yl)-4-oxoquinoline-3-carboxylic acid
• CAS号：108461-05-8
• 分子式：C₂₀H₂₂FN₃O₃
• 分子量：371.40500
• 发布时间：2016-02-28 22:24:06
• 更新时间：2024-01-18 15:55:23

名称

• 英文名: 1-cyclopropyl-6-fluoro-7-(8-methyl-3,8-diazabicyclo[3.2.1]octan-3-yl)-4-oxoquinoline-3-carboxylic acid
• 英文别名: 3-Quinolinecarboxylicacid,1-cyclopropyl-6-fluoro-1,4-dihydro-7-(8-methyl-3,8-diazabicyclo[3.2.1]oct-3-yl)-4-oxo; 1-cyclopropyl-6-fluoro-1,4-dihydro-7-(8-methyl-3,8-diazabicyclo[3.2.1]oct-3-yl)-4-oxo-3-quinoline carboxylic acid; CP-74,667

物化性质

• 密度: 1.438g/cm3
• 沸点: 577.9ºC at 760mmHg
• 分子式: C₂₀H₂₂FN₃O₃
• 分子量: 371.40500
• 闪点: 303.3ºC
• 精确质量: 371.16500
• PSA: 65.78000
• LogP: 2.45940
• 蒸汽压: 3.39E-14mmHg at 25°C
• 折射率: 1.66

合成路线

93107-30-3 17783-50-5 ~84% 108461-05-8

文献：McGuirk; Jefson; Mann; Elliott; Chang; Cisek; Cornell; Gootz; Haskell; Hindahl; LaFleur; Rosenfeld; Shryock; Silvia; Weber Journal of Medicinal Chemistry, 1992 , vol. 35, # 4 p. 611 - 620