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4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol

更新时间:2024-01-14 15:13:26

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol结构式
4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol结构式
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常用名 4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol 英文名 4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol
CAS号 112668-45-8 分子量 256.30300
密度 1.34g/cm3 沸点 513.6ºC at 760 mmHg
分子式 C14H16N4O 熔点 N/A
MSDS N/A 闪点 264.4ºC

 名称

英文名 1-(4-aminoimidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
英文别名 更多

 物理化学性质

密度 1.34g/cm3
沸点 513.6ºC at 760 mmHg
分子式 C14H16N4O
分子量 256.30300
闪点 264.4ºC
精确质量 256.13200
PSA 77.69000
LogP 1.86770
蒸汽压 2.26E-11mmHg at 25°C
折射率 1.685

 合成线路

~%

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol结构式

4-amino-alpha,a...

112668-45-8

文献:Riker Laboratories, Inc. Patent: US4689338 A1, 1987 ; US 4689338 A

~%

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol结构式

4-amino-alpha,a...

112668-45-8

文献:Minnesota Mining and Manufacturing Company Patent: US5741908 A1, 1998 ;

~86%

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol结构式

4-amino-alpha,a...

112668-45-8

文献:Shi, Ce; Xiong, Zhengming; Chittepu, Padmaja; Aldrich, Courtney C.; Ohlfest, John R.; Ferguson, David M. ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 6 p. 501 - 504

~%

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol结构式

4-amino-alpha,a...

112668-45-8

文献:Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

~%

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol结构式

4-amino-alpha,a...

112668-45-8

文献:Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

~%

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol结构式

4-amino-alpha,a...

112668-45-8

文献:Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

~%

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol结构式

4-amino-alpha,a...

112668-45-8

文献:Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

~%

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol结构式

4-amino-alpha,a...

112668-45-8

文献:Shi, Ce; Xiong, Zhengming; Chittepu, Padmaja; Aldrich, Courtney C.; Ohlfest, John R.; Ferguson, David M. ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 6 p. 501 - 504

 英文别名

4-amino-1-(2-hydroxy-2-methylpropyl)-1H-imidazo[4,5-c]quinoline
2-Hydroxy Imiquimod
R 842
1-(2,hydroxy-2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine
1-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol