2-吡啶肟甲磺酸甲酯

• 常用名: 2-吡啶肟甲磺酸甲酯
• 英文名: pralidoxime mesilate
• CAS号: 154-97-2
• 分子量: 232.25700
• 密度: N/A
• 沸点: 189.7ºC at 760mmHg
• 分子式: C₈H₁₂N₂O₄S
• 熔点: N/A
• 闪点: 68.5ºC

2-吡啶肟甲磺酸甲酯名称

• 中文名: 2-吡啶肟甲磺酸甲酯
• 英文名: pralidoxime mesylate
• 中文别名: 吡啶-2-醛肟甲基甲磺酸酯

2-吡啶肟甲磺酸甲酯物理化学性质

• 沸点: 189.7ºC at 760mmHg
• 分子式: C₈H₁₂N₂O₄S
• 分子量: 232.25700
• 闪点: 68.5ºC
• 精确质量: 232.05200
• PSA: 102.05000
• LogP: 0.56140
• 储存条件:

  2-8℃。

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:1

  3.氢键受体数量:5

  4.可旋转化学键数量:1

  5.互变异构体数量:无

  6.拓扑分子极性表面积99.9

  7.重原子数量:15

  8.表面电荷:0

  9.复杂度:295

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:1

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:2

2-吡啶肟甲磺酸甲酯MSDS

Date Updated: 11/FEB/2006
Version 1.2
Regulation (EC) No 1907/2006
________________________________________________________________________
1 - Product and Company Information
________________________________________________________________________

Product NamePYRIDINE-2-ALDOXIME METHYL
METHANESULFONATE
Product NumberP0268
Company
Century Ba-Shi Building 22A-B,
200020 Shanghai
Technical Phone #86-21-61415566
Fax 86-21-61415567
E-mail Address
________________________________________________________________________
2 - Hazards Identification
________________________________________________________________________
________________________________________________________________________
3 - Composition/Information on Ingredients
________________________________________________________________________
Product NameCAS #EC noAnnex I
Index Number
2-PYRIDINEALDOXIME METHYL154-97-2 205-839-8 None
METHANE-SULFONATE, 95%
FormulaC7H9N2O.CH3O3S
Molecular Weight 232,2600 AMU
SynonymsContrathion * 2-Formyl-N-methylpyridinium oxime
methanesulfonat * 2-Formyl-1-methylpyridinium
methanesulfonate oxim *
2-Hydroxyiminomethyl-N-methylpyridinium
methanesulphonate *
N-Methylpyridinium-2-aldoxime methanesulphonate
* 1-Methylpyridinium-2-aldoxime methanesulfonate
* N-Methylpyridinium methane sulfonate
2-aldoxime * 2-Pam methanesulfonate *
Pralidoxime mesylate * Pralidoxime
methanesulfonate * Pralidoxime methosulfate *
Protopam methanesulfonate * P2S * Pyridinium,
2-aldoxime, N-methyl methanesulphonat *
Pyridinium, 2-((hydroxyimino)methyl)-1-methyl-,
methanesulfonate (salt) (9CI)
________________________________________________________________________
4 - First Aid Measures
________________________________________________________________________
AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
________________________________________________________________________
5 - Fire Fighting Measures
________________________________________________________________________
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
________________________________________________________________________
6 - Accidental Release Measures
________________________________________________________________________
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear protective equipment.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
________________________________________________________________________
7 - Handling and Storage
________________________________________________________________________
STORAGE
Store at 2-8°C
________________________________________________________________________
8 - Exposure Controls / Personal Protection
________________________________________________________________________
ENGINEERING CONTROLS
Mechanical exhaust required.
PERSONAL PROTECTIVE EQUIPMENT
Special Protective Measures: Wear appropriate government approved
respirator, chemical-resistant gloves, safety goggles, other
protective clothing.
________________________________________________________________________
9 - Physical and Chemical Properties
________________________________________________________________________
pH N/A
BP/BP RangeN/A
MP/MP Range154,000. - 156,000 °
C.
Flash PointN/A
FlammabilityN/A
Autoignition TempN/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion LimitsN/A
Vapor PressureN/A
Partition Coefficient N/A
ViscosityN/A
Vapor DensityN/A
Saturated Vapor Conc. N/A
Evaporation RateN/A
Bulk DensityN/A
Decomposition Temp.N/A
Solvent ContentN/A
Water ContentN/A
Surface TensionN/A
ConductivityN/A
Miscellaneous DataN/A
SolubilityN/A
________________________________________________________________________
10 - Stability and Reactivity
________________________________________________________________________
STABILITY
Stable: Stable.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides, Sulfur oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
________________________________________________________________________
11 - Toxicological Information
________________________________________________________________________
RTECS NUMBER: UU4570000
ACUTE TOXICITY
LD50
Oral
Rat
7000,000000 mg/kg
LD50
Intraperitoneal
Rat
262 MG/KG
Remarks: Lungs, Thorax, or Respiration:Dyspnea.
Behavioral:Convulsions or effect on seizure threshold.
Behavioral:Tremor.
LD50
Subcutaneous
Rat
332 MG/KG
Remarks: Lungs, Thorax, or Respiration:Dyspnea.
Behavioral:Convulsions or effect on seizure threshold.
Behavioral:Tremor.
LD50
Intravenous
Rat
109 MG/KG
Remarks: Lungs, Thorax, or Respiration:Dyspnea.
Behavioral:Convulsions or effect on seizure threshold.
Behavioral:Tremor.
LD50
Oral
Mouse
3700,000000 mg/kg
LD50
Intraperitoneal
Mouse
132 MG/KG
LD50
Subcutaneous
Mouse
165 MG/KG
Remarks: Lungs, Thorax, or Respiration:Dyspnea.
Behavioral:Convulsions or effect on seizure threshold.
Behavioral:Tremor.
LD50
Intravenous
Mouse
118 MG/KG
LD50
Intramuscular
Monkey
356 MG/KG
Remarks: Behavioral:Tremor. Behavioral:Convulsions or effect on
seizure threshold. Lungs, Thorax, or Respiration:Dyspnea.
LD50
Intravenous
Rabbit
118 MG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Behavioral:Muscle weakness. Lungs, Thorax, or
Respiration:Cyanosis.
LD50
Intramuscular
Rabbit
258 MG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Behavioral:Muscle weakness. Lungs, Thorax, or
Respiration:Cyanosis.
ROUTE OF EXPOSURE
Multiple Routes: May cause irritation. May be harmful by
inhalation, ingestion, or skin absorption.
CONDITIONS AGGRAVATED BY EXPOSURE
The toxicological properties have not been thoroughly
investigated.
________________________________________________________________________
12 - Ecological Information
________________________________________________________________________
No data available.
________________________________________________________________________
13 - Disposal Considerations
________________________________________________________________________
SUBSTANCE DISPOSAL
Dissolve or mix the material with a combustible solvent and burn
in a chemical incinerator equipped with an afterburner and
scrubber. Observe all federal, state, and local environmental
regulations.
________________________________________________________________________
14 - Transport Information
________________________________________________________________________
RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.
________________________________________________________________________
15 - Regulatory Information
________________________________________________________________________
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 2
Self-Classification
________________________________________________________________________
16 - Other Information
________________________________________________________________________
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
unlimitedpaper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.

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模块 15 - 法规信息
N/A

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模块16 - 其他信息
N/A

2-吡啶肟甲磺酸甲酯毒性和生态

2-吡啶肟甲磺酸甲酯英文别名

• protopammethanesulfonate
• pralidoximemethosulfate
• 2-(hydroxyimino-methyl)-1-methyl-pyridinium,methanesulfonate
• contrathion
• pralidoxime mesilate
• pralidoxime methanesulphonate
• pralidoximemesylate
• Pralidoxime methylsulfate
• 2-(Hydroxyimino-methyl)-1-methyl-pyridinium,Methansulfonat
• 2-PYRIDINEALDOXIME METHYL METHANESULFONATE
• Pralidoxime
• p2s
• pyridine-2-aldoxime methyl methanesulfonate
• Einecs 205-839-8
• 2-pammethanesulfonate