FM-381

• 常用名: FM-381
• 英文名: FM-381
• CAS号: 2226521-65-7
• 分子量: 428.486
• 密度: 1.4±0.1 g/cm3
• 沸点: 749.8±70.0 °C at 760 mmHg
• 分子式: C₂₄H₂₄N₆O₂
• 熔点: N/A
• 闪点: 407.3±35.7 °C

FM-381用途

FM-381 is a JAK3 specific reversible covalent inhibitor with IC50 of 127 pM for JAK3 and demonstrates 400-, 2,700- and 3,600-fold selectivity over JAK1, JAK2, and TYK2, respectively.

FM-381名称

• 英文名: FM-381

FM-381物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 749.8±70.0 °C at 760 mmHg
• 分子式: C₂₄H₂₄N₆O₂
• 分子量: 428.486
• 闪点: 407.3±35.7 °C
• 精确质量: 428.196075
• LogP: 3.77
• 外观性状: powder.white to beige
• 蒸汽压: 0.0±2.5 mmHg at 25°C
• 折射率: 1.709
• 储存条件: 2-8°C

FM-381英文别名

• (2E)-2-Cyano-3-[5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-2-furyl]-N,N-dimethylacrylamide
• (E)-2-Cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide
• 2-Cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide
• 2-Propenamide, 2-cyano-3-[5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-2-furanyl]-N,N-dimethyl-, (2E)-
• MFCD31630713