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2(1H)-Quinazolinone,6-chloro-3-ethyl-3,4-dihydro-4-hydroxy-4-phenyl-

更新时间:2024-01-11 15:55:38

2(1H)-Quinazolinone,6-chloro-3-ethyl-3,4-dihydro-4-hydroxy-4-phenyl-结构式
2(1H)-Quinazolinone,6-chloro-3-ethyl-3,4-dihydro-4-hydroxy-4-phenyl-结构式
委托求购
常用名 2(1H)-Quinazolinone,6-chloro-3-ethyl-3,4-dihydro-4-hydroxy-4-phenyl- 英文名 2(1H)-Quinazolinone,6-chloro-3-ethyl-3,4-dihydro-4-hydroxy-4-phenyl-
CAS号 25514-11-8 分子量 302.75600
密度 1.322g/cm3 沸点 537.6ºC at 760mmHg
分子式 C16H15ClN2O2 熔点 N/A
MSDS N/A 闪点 279ºC

 名称

英文名 6-chloro-3-ethyl-4-hydroxy-4-phenyl-1H-quinazolin-2-one
英文别名 更多

 物理化学性质

密度 1.322g/cm3
沸点 537.6ºC at 760mmHg
分子式 C16H15ClN2O2
分子量 302.75600
闪点 279ºC
精确质量 302.08200
PSA 52.57000
LogP 3.47670
蒸汽压 2.17E-12mmHg at 25°C
折射率 1.625

 合成线路

~89%

2(1H)-Quinazolinone,6-chloro-3-ethyl-3,4-dihydro-4-hydroxy-4-phenyl-结构式

2(1H)-Quinazoli...

25514-11-8

文献:Yamamoto Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 8 p. 2135 - 2156

~84%

2(1H)-Quinazolinone,6-chloro-3-ethyl-3,4-dihydro-4-hydroxy-4-phenyl-结构式

2(1H)-Quinazoli...

25514-11-8

文献:E. I. Du Pont de Nemours and Company Patent: US4258187 A1, 1981 ;

~%

2(1H)-Quinazolinone,6-chloro-3-ethyl-3,4-dihydro-4-hydroxy-4-phenyl-结构式

2(1H)-Quinazoli...

25514-11-8

文献:Yamamoto Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 8 p. 2135 - 2156

~%

2(1H)-Quinazolinone,6-chloro-3-ethyl-3,4-dihydro-4-hydroxy-4-phenyl-结构式

2(1H)-Quinazoli...

25514-11-8

文献:Barrow, James C.; Rittle, Kenneth E.; Reger, Thomas S.; Yang, Zhi-Qiang; Bondiskey, Phung; McGaughey, Georgia B.; Bock, Mark G.; Hartman, George D.; Tang, Cuyue; Ballard, Jeanine; Kuo, Yuhsin; Prueksaritanont, Thomayant; Nuss, Cindy E.; Doran, Scott M.; Fox, Steven V.; Garson, Susan L.; Kraus, Richard L.; Li, Yuxing; Marino, Michael J.; Kuzmick Graufelds, Valerie; Uebele, Victor N.; Renger, John J. ACS Medicinal Chemistry Letters, 2010 , vol. 1, # 2 p. 75 - 79

~%

2(1H)-Quinazolinone,6-chloro-3-ethyl-3,4-dihydro-4-hydroxy-4-phenyl-结构式

2(1H)-Quinazoli...

25514-11-8

文献:Schleuder, M.; Richter, P.; Brandner, Anke; Morgenstern O. Pharmazie, 1989 , vol. 44, # 4 p. 259 - 260

~%

2(1H)-Quinazolinone,6-chloro-3-ethyl-3,4-dihydro-4-hydroxy-4-phenyl-结构式

2(1H)-Quinazoli...

25514-11-8

文献:Schleuder, M.; Richter, P.; Brandner, Anke; Morgenstern O. Pharmazie, 1989 , vol. 44, # 4 p. 259 - 260

 英文别名

6-chloro-3-ethyl-4-hydroxy-4-phenyl-3,4-dihydro-1H-quinazolin-2-one