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PhTX-433

更新时间:2024-01-16 12:31:13

PhTX-433结构式
PhTX-433结构式
品牌特惠专场
常用名 PhTX-433 英文名 PhTX-433
CAS号 276684-27-6 分子量 777.67300
密度 N/A 沸点 N/A
分子式 C29H44F9N5O9 熔点 N/A
MSDS 美版 闪点 N/A
符号 GHS06
GHS06
信号词 Danger

 PhTX-433用途


PhTX-433, also known as Philanthotoxin 433, is a polyamine-containing toxin, which blocks NMDA-gated ion channels; originally isolated from the venom of the wasp Philanthus triangulum.

 PhTX-433名称

英文名 N-[(2S)-1-[4-[3-(3-aminopropylamino)propylamino]butylamino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]butanamide,2,2,2-trifluoroacetic acid
英文别名 更多

 PhTX-433物理化学性质

分子式 C29H44F9N5O9
分子量 777.67300
精确质量 777.30000
PSA 247.39000
LogP 6.09670

 PhTX-433安全信息

符号 GHS06
GHS06
信号词 Danger
危害声明 H301
警示性声明 P301 + P310
个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码 UN 2811 6.1/PG 2

 PhTX-433文献4

更多文献
Effects of philanthotoxin-343 on CA1 pyramidal neurons of rat hippocampus in vitro.

Eur. J. Pharmacol. 228 , 201-206, (1992)

A synthetic analog of philanthotoxin-433, philanthotoxin-343 (PhTX-343), was tested in hippocampal pyramidal neurons in vitro. PhTX-343 (2 microM) did not significantly change synaptic transmission me...

Philanthotoxin inhibits Ca2+ currents in rat hippocampal CA1 neurons.

Eur. J. Pharmacol. 270 , 357-360, (1994)

The wasp venom philanthotoxin-4.3.3 (PhTX-4.3.3) is an antagonist of glutamate transmission in the insect as well as in the mammalian brain. It was recently shown that PhTX-4.3.3 inhibits the N-methyl...

Inhibition of dipteran larval neuromuscular synaptic transmission by analogues of philanthotoxin-4.3.3: a structure-activity study.

Comp. Biochem. Physiol. 102C , 267-272, (1992)

1. The blocking action of delta-philanthotoxin (PhTX-4.3.3), a wasp toxin composed of a polyamine chain, an aromatic amino acid (tyrosyl) nucleus and an aliphatic (butanoic) acid was studied, together...

 PhTX-433英文别名

(S)-N-[4-[[3-[(3-Aminopropyl)amino]propyl]amino]butyl]-4-hydroxy-|A-[(1-oxobutyl)amino]benzenepropanamide tris(trifluoroacetate) salt
Philanthotoxin 433 tris(trifluoroacetate) salt
PhTX-433 tris(trifluoroacetate) salt
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