7-氯-5-(2-氯苯基)-1,3-二氢-2-氧代-2H-1,4-苯并二氮杂卓-3-基乙酸酯
7-氯-5-(2-氯苯基)-1,3-二氢-2-氧代-2H-1,4-苯并二氮杂卓-3-基乙酸酯结构式
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常用名 | 7-氯-5-(2-氯苯基)-1,3-二氢-2-氧代-2H-1,4-苯并二氮杂卓-3-基乙酸酯 | 英文名 | 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2-oxo-2H-1,4-benzodiazepin-3-yl acetate |
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| CAS号 | 2848-96-6 | 分子量 | 363.19500 | |
| 密度 | 1.45 g/cm3 | 沸点 | 524.4ºC at 760 mmHg | |
| 分子式 | C17H12Cl2N2O3 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | 270.9ºC | |
| 符号 |
GHS07, GHS09 |
信号词 | Warning |
| 中文名 | 7-氯-5-(2-氯苯基)-1,3-二氢-2-氧代-2H-1,4-苯并二氮杂卓-3-基乙酸酯 |
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| 英文名 | [7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl] acetate |
| 中文别名 | 氯羟安定杂质A |
| 英文别名 | 更多 |
| 密度 | 1.45 g/cm3 |
|---|---|
| 沸点 | 524.4ºC at 760 mmHg |
| 分子式 | C17H12Cl2N2O3 |
| 分子量 | 363.19500 |
| 闪点 | 270.9ºC |
| 精确质量 | 362.02200 |
| PSA | 67.76000 |
| LogP | 3.24570 |
| 蒸汽压 | 4.33E-11mmHg at 25°C |
| 折射率 | 1.656 |
| 符号 |
GHS07, GHS09 |
|---|---|
| 信号词 | Warning |
| 危害声明 | H302-H410 |
| 警示性声明 | P273-P501 |
| 危险品运输编码 | UN 3077 9 / PGIII |
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~90%
7-氯-5-(2-氯苯基)-1... 2848-96-6 |
| 文献：Cepanec, Ivica; Litvic, Mladen; Pogorelic, Ivan Organic Process Research and Development, 2006 , vol. 10, # 6 p. 1192 - 1198 |
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~%
7-氯-5-(2-氯苯基)-1... 2848-96-6 |
| 文献：Cepanec, Ivica; Litvic, Mladen; Pogorelic, Ivan Organic Process Research and Development, 2006 , vol. 10, # 6 p. 1192 - 1198 |
|
~%
7-氯-5-(2-氯苯基)-1... 2848-96-6 |
| 文献：Cepanec, Ivica; Litvic, Mladen; Pogorelic, Ivan Organic Process Research and Development, 2006 , vol. 10, # 6 p. 1192 - 1198 |
CAS号846-49-1|
Stereoselective binding of 3-acetoxy-, and 3-hydroxy-1,4-benzodiazepine-2-ones to human serum albumin. Selective allosteric interaction with warfarin enantiomers.
Biochem. Pharmacol. 35(2) , 263-9, (1986) Stereoselective binding of oxazepam, lorazepam, temazepam and methyl lorazepam as well as of their acetates to human serum albumin was investigated by different techniques. The 2'-chlorine and the N(1... |
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Stereoselective kinetics of warfarin binding to human serum albumin: effect of an allosteric interaction.
Chirality 14(5) , 442-8, (2002) Kinetic and equilibrium binding studies were performed on the interaction of warfarin enantiomers with human serum albumin (HSA) in the absence and presence of lorazepam acetate (LoAc) enantiomers. Bi... |
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Stereoselective allosteric binding interaction on human serum albumin between ibuprofen and lorazepam acetate.
Chirality 11(2) , 115-20, (1999) The effect of ibuprofen enantiomers on the stereoselective binding of 3-acyloxy-1,4-benzodiazepines to human serum albumin (HSA) was studied using both native and Sepharose-immobilized protein. (S)-Lo... |
| lorazepam acetate |
