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Brecanavir

更新时间：2024-01-09 15:10:20

Brecanavir结构式	常用名	Brecanavir	英文名	Brecanavir
	CAS号	313682-08-5	分子量	703.82300
	密度	1.43g/cm3	沸点	N/A
	分子式	C₃₃H₄₁N₃O₁₀S₂	熔点	N/A
	MSDS	N/A	闪点	N/A

Brecanavir用途

Brecanavir(GW640385)是一种新型、有效的HIV蛋白酶抑制剂。

中文名	GW640385
英文名	[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxy-1-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]butan-2-yl]carbamate
英文别名	更多

描述

Brecanavir(GW640385)是一种新型、有效的HIV蛋白酶抑制剂。

相关类别

研究领域 >> 感染

信号通路 >> 代谢酶/蛋白酶 >> HIV蛋白酶

参考文献

[1]. Ford SL, Reddy YS, Anderson MT, et al. Single-dose safety and pharmacokinetics of brecanavir, a novel human immunodeficiency virus protease inhibitor. Antimicrob Agents Chemother. 2006;50(6):2201-2206.

[2]. Reddy YS, Ford SL, Anderson MT, Murray SC, Ng-Cashin J, Johnson MA. Safety and pharmacokinetics of brecanavir, a novel human immunodeficiency virus type 1 protease inhibitor, following repeat administration with and without ritonavir in healthy adult subjects. Antimicrob Agents Chemother. 2007;51(4):1202-1208.

密度	1.43g/cm3
分子式	C₃₃H₄₁N₃O₁₀S₂
分子量	703.82300
精确质量	703.22300
PSA	191.60000
LogP	5.33740
折射率	1.641
储存条件	2-8°C，密封，干燥

(3R,3AS,6AR)-hexahydrofuro[2,3-b]furan-3-yl (1S,2R)-3-[(1,3-benzodioxol-5-ylsulfonyl)(isobutyl)amino]-1-[4-(benzyloxy)benzyl]-2-hydroxypropylcarbamate结构式

(3R,3AS,6AR)-he...

313679-55-9

~%

Brecanavir结构式

Brecanavir

313682-08-5

文献：Miller, John F.; Andrews, C. Webster; Brieger, Michael; Furfine, Eric S.; Hale, Michael R.; Hanlon, Mary H.; Hazen, Richard J.; Kaldor, Istvan; McLean, Ed W.; Reynolds, David; Sammond, Douglas M.; Spaltenstein, Andrew; Tung, Roger; Turner, Elizabeth M.; Xu, Robert X.; Sherrill, Ronald G. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 7 p. 1788 - 1794

N-(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl-oxycarbonyl-, (4S,5R)-4-(4-benzyloxy-benzyl)-5-i-butyl-[(3,4-methylenedioxyphenyl)sulfonyl]-aminomethyl-2,2-dimethyl-oxazolidine结构式

N-(3R,3aS,6aR)-...

313682-03-0

~%

Brecanavir结构式

Brecanavir

313682-08-5

文献：Miller, John F.; Andrews, C. Webster; Brieger, Michael; Furfine, Eric S.; Hale, Michael R.; Hanlon, Mary H.; Hazen, Richard J.; Kaldor, Istvan; McLean, Ed W.; Reynolds, David; Sammond, Douglas M.; Spaltenstein, Andrew; Tung, Roger; Turner, Elizabeth M.; Xu, Robert X.; Sherrill, Ronald G. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 7 p. 1788 - 1794

未登录结构式

未登录

313682-07-4

~%

Brecanavir结构式

Brecanavir

313682-08-5

文献：Miller, John F.; Andrews, C. Webster; Brieger, Michael; Furfine, Eric S.; Hale, Michael R.; Hanlon, Mary H.; Hazen, Richard J.; Kaldor, Istvan; McLean, Ed W.; Reynolds, David; Sammond, Douglas M.; Spaltenstein, Andrew; Tung, Roger; Turner, Elizabeth M.; Xu, Robert X.; Sherrill, Ronald G. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 7 p. 1788 - 1794

(3R,3aS,6aR)hexahydrofuro[2,3-b]furan-3-yl (4S,5R)-5-{[(1,3-benzodioxol-5-ylsulfonyl)(isobutyl)amino]methyl}-4-(4-hydroxybenzyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate结构式

(3R,3aS,6aR)hex...

313681-84-4

~%

Brecanavir结构式

Brecanavir

313682-08-5

文献：Miller, John F.; Andrews, C. Webster; Brieger, Michael; Furfine, Eric S.; Hale, Michael R.; Hanlon, Mary H.; Hazen, Richard J.; Kaldor, Istvan; McLean, Ed W.; Reynolds, David; Sammond, Douglas M.; Spaltenstein, Andrew; Tung, Roger; Turner, Elizabeth M.; Xu, Robert X.; Sherrill, Ronald G. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 7 p. 1788 - 1794

Brecanavir

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2fde

GW0385

上海化源世纪贸易有限公司
上海市上海市普陀区
产品名：GW640385
纯度：98.0%
规格：
联系人：徐经理
联系电话：13311869306

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Brecanavir生产厂家

Brecanavir价格