Lorazepam glucuronide

更新时间：2025-08-21 16:42:52

Lorazepam glucuronide结构式	常用名	Lorazepam glucuronide	英文名	Lorazepam glucuronide
	CAS号	32781-79-6	分子量	497.28200
	密度	1.76g/cm3	沸点	779.5ºC at 760mmHg
	分子式	C₂₁H₁₈Cl₂N₂O₈	熔点	N/A
	MSDS	N/A	闪点	425.2ºC
	符号	GHS02, GHS07	信号词	Danger

英文名	Lorazepam glucuronide
英文别名	更多

密度	1.76g/cm3
沸点	779.5ºC at 760mmHg
分子式	C₂₁H₁₈Cl₂N₂O₈
分子量	497.28200
闪点	425.2ºC
精确质量	496.04400
PSA	157.91000
LogP	0.59140
InChIKey	IWOJSSFCRQKNKN-IFBJMGMISA-N
SMILES	O=C1Nc2ccc(Cl)cc2C(c2ccccc2Cl)=NC1OC1OC(C(=O)O)C(O)C(O)C1O
折射率	1.731

符号	GHS02, GHS07
信号词	Danger
危害声明	H225-H302-H319
警示性声明	P210-P305 + P351 + P338
危险品运输编码	UN 1648 3 / PGII

Commentary on: Dou C, Bournique J, Zinda M, Gnezda M, Nally A, Salamone S. Comparison of rates of hydrolysis of lorazepam-glucuronide, oxazepam-glucuronide and temazepam-glucuronide catalyzed by E. coli beta-glucuronidase using the on-line benzodiazepine screening immunoassay on the Roche/Hitachi 917 analyzer.

J. Forensic Sci. 47(2) , 427-8, (2002)

Population pharmacokinetics of lorazepam and midazolam and their metabolites in intensive care patients on continuous venovenous hemofiltration.

Am. J. Kidney Dis. 45(2) , 360-71, (2005)

The objective is to study the population pharmacokinetics of lorazepam and midazolam in critically ill patients with acute renal failure who are treated with continuous venovenous hemofiltration (CVVH...

Biotransformation and excretion of lorazepam in patients with chronic renal failure.

Br. J. Clin. Pharmacol. 3(6) , 1033-9, (1976)

To evaluate the effect of end-stage renal insufficiency and haemodialysis on the elimination of lorazepam, single oral doses of the drug (2.5 mg) were administered to normal subjects and patients with...

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