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1-(S)-adamantan-1-yl-(R)-(2-hydroxy-1-phenylethylamino)acetonitrile

更新时间:2024-01-29 19:16:04

1-(S)-adamantan-1-yl-(R)-(2-hydroxy-1-phenylethylamino)acetonitrile结构式
1-(S)-adamantan-1-yl-(R)-(2-hydroxy-1-phenylethylamino)acetonitrile结构式
品牌特惠专场
常用名 1-(S)-adamantan-1-yl-(R)-(2-hydroxy-1-phenylethylamino)acetonitrile 英文名 1-(S)-adamantan-1-yl-(R)-(2-hydroxy-1-phenylethylamino)acetonitrile
CAS号 361441-95-4 分子量 310.433
密度 1.2±0.1 g/cm3 沸点 511.0±35.0 °C at 760 mmHg
分子式 C20H26N2O 熔点 N/A
MSDS N/A 闪点 262.8±25.9 °C

 名称

英文名 (2S)-2-(1-adamantyl)-2-[[(1R)-2-hydroxy-1-phenylethyl]amino]acetonitrile
英文别名 更多

 物理化学性质

密度 1.2±0.1 g/cm3
沸点 511.0±35.0 °C at 760 mmHg
分子式 C20H26N2O
分子量 310.433
闪点 262.8±25.9 °C
精确质量 310.204498
PSA 56.05000
LogP 4.16
蒸汽压 0.0±1.4 mmHg at 25°C
折射率 1.599

 合成线路

~64%

1-(S)-adamantan-1-yl-(R)-(2-hydroxy-1-phenylethylamino)acetonitrile结构式

1-(S)-adamantan...

361441-95-4

文献:BRISTOL-MYERS SQUIBB COMPANY Patent: WO2005/12249 A2, 2005 ; Location in patent: Page/Page column 35 ; WO 2005/012249 A2

~61%

1-(S)-adamantan-1-yl-(R)-(2-hydroxy-1-phenylethylamino)acetonitrile结构式

1-(S)-adamantan...

361441-95-4

文献:Dong, Jizhe; Gong, Yanchun; Liu, Jun; Chen, Xiangfeng; Wen, Xiaoan; Sun, Hongbin Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 4 p. 1383 - 1393

~%

1-(S)-adamantan-1-yl-(R)-(2-hydroxy-1-phenylethylamino)acetonitrile结构式

1-(S)-adamantan...

361441-95-4

文献:LEE PHARMA LIMITED; ALLA, Venkat Reddy; ALLA, Raghu Mitra; DUBEY, Ajay Kumar; REDDY, P. Ramakrishna Patent: WO2014/57495 A1, 2014 ;

~%

1-(S)-adamantan-1-yl-(R)-(2-hydroxy-1-phenylethylamino)acetonitrile结构式

1-(S)-adamantan...

361441-95-4

文献:LEE PHARMA LIMITED; ALLA, Venkat Reddy; ALLA, Raghu Mitra; DUBEY, Ajay Kumar; REDDY, P. Ramakrishna Patent: WO2014/57495 A1, 2014 ;

~%

1-(S)-adamantan-1-yl-(R)-(2-hydroxy-1-phenylethylamino)acetonitrile结构式

1-(S)-adamantan...

361441-95-4

文献:LEE PHARMA LIMITED; ALLA, Venkat Reddy; ALLA, Raghu Mitra; DUBEY, Ajay Kumar; REDDY, P. Ramakrishna Patent: WO2014/57495 A1, 2014 ;

 英文别名

TRI015
2-(S)-adamantan-1-yl-(R)-(2-hydroxy-1-phenylethylamino)acetonitrile
(2S)-Adamantan-1-yl{[(1R)-2-hydroxy-1-phenylethyl]amino}acetonitrile
Tricyclo[3.3.1.1]decane-1-acetonitrile, α-[[(1R)-2-hydroxy-1-phenylethyl]amino]-, (αS)-
1-(S)-adamantan-1-yl-(R)-(2-hydroxy-1-phenylethylamino)acetonitrile