前往化源商城

4,4-Difluoro-3,3-dimethyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}- L-proline

更新时间:2024-01-20 17:38:55

4,4-Difluoro-3,3-dimethyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}- L-proline结构式
4,4-Difluoro-3,3-dimethyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}- L-proline结构式
品牌特惠专场
常用名 4,4-Difluoro-3,3-dimethyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}- L-proline 英文名 4,4-Difluoro-3,3-dimethyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}- L-proline
CAS号 478698-32-7 分子量 279.28000
密度 1.24g/cm3 沸点 348.6ºC at 760 mmHg
分子式 C12H19F2NO4 熔点 N/A
MSDS N/A 闪点 N/A

 名称

英文名 4,4-Difluoro-3,3-dimethyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}- L-proline
英文别名 更多

 物理化学性质

密度 1.24g/cm3
沸点 348.6ºC at 760 mmHg
分子式 C12H19F2NO4
分子量 279.28000
精确质量 279.12800
PSA 66.84000
LogP 2.28970
折射率 1.474

 合成线路

~68%

4,4-Difluoro-3,3-dimethyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}- L-proline结构式

4,4-Difluoro-3,...

478698-32-7

文献:Hu, Shanghui; Martinez, Carlos A.; Kline, Billie; Yazbeck, Daniel; Tao, Junhua; Kucera, David J. Organic Process Research and Development, 2006 , vol. 10, # 3 p. 650 - 654

~95%

4,4-Difluoro-3,3-dimethyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}- L-proline结构式

4,4-Difluoro-3,...

478698-32-7

文献:Agouron Pharmaceuticals, Inc. Patent: US2004/204591 A1, 2004 ;

~%

4,4-Difluoro-3,3-dimethyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}- L-proline结构式

4,4-Difluoro-3,...

478698-32-7

文献:Rossi, Francesco; Corcella, Francesco; Caldarelli, Francesco Saverio; Heidempergher, Franco; Marchionni, Chiara; Auguadro, Miriam; Cattaneo, Marco; Ceriani, Lucio; Visentin, Giuseppina; Ventrella, Giambattista; Pinciroli, Vittorio; Ramella, Giuliano; Candiani, Ilaria; Bedeschi, Angelo; Tomasi, Attilio; Kline, Billie J.; Martinez, Carlos A.; Yazbeck, Daniel; Kucera, David J. Organic Process Research and Development, 2008 , vol. 12, # 2 p. 322 - 338

~%

4,4-Difluoro-3,3-dimethyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}- L-proline结构式

4,4-Difluoro-3,...

478698-32-7

文献:Hu, Shanghui; Martinez, Carlos A.; Kline, Billie; Yazbeck, Daniel; Tao, Junhua; Kucera, David J. Organic Process Research and Development, 2006 , vol. 10, # 3 p. 650 - 654

 英文别名

(2S)-4,4-difluoro-3,3-dimethyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
1-hydroxymethyl-4-(4-(1,1-dimethylethoxycarbonyl)piperazinyl)benzene
1-(tert-Butoxycarbonyl)-4-(4-hydroxymethylphenyl)piperazine
4,4-difluoro-3,3-dimethyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
TERT-BUTYL 4-[4-(HYDROXYMETHYL)PHENYL]TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE
(2S)-4,4-difluoro-3,3-dimethyl-N-Boc-proline
4-[4-(methoxycarbonyl)phenyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
1-(tert-butoxycarbonyl)-4-(4-methoxycarbonylphenyl)piperazine
4-(4-N-Boc-piperazinyl)benzyl alcohol
4-(4-methoxycarbonyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester
Methyl 4-(N-Boc-N'-piperazinyl)benzoate
1-(tert-butoxycarbonyl)-4,4-difluoro-3,3-dimethylpyrrolidine-2-carboxylic acid
tert-butyl 4-(4-(methoxycarbonyl)phenyl)piperazine-1-carboxylate
tert-butyl 4-(4-(hydroxymethyl)phenyl)piperazine-1-carboxylate