(2R)-2-(3-chloro-4-methylsulfonylphenyl)-3-[(1R)-3-oxocyclopentyl]-N-pyrazin-2-ylpropanamide结构式
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常用名 | (2R)-2-(3-chloro-4-methylsulfonylphenyl)-3-[(1R)-3-oxocyclopentyl]-N-pyrazin-2-ylpropanamide | 英文名 | (2R)-2-(3-chloro-4-methylsulfonylphenyl)-3-[(1R)-3-oxocyclopentyl]-N-pyrazin-2-ylpropanamide |
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CAS号 | 625114-41-2 | 分子量 | 421.89800 | |
密度 | N/A | 沸点 | N/A | |
分子式 | C19H20ClN3O4S | 熔点 | N/A | |
MSDS | N/A | 闪点 | N/A |
用途Piragliatin (RO 4389620. |
英文名 | (2R)-2-(3-chloro-4-methylsulfonylphenyl)-3-[(1R)-3-oxocyclopentyl]-N-pyrazin-2-ylpropanamide |
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英文别名 | 更多 |
分子式 | C19H20ClN3O4S |
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分子量 | 421.89800 |
精确质量 | 421.08600 |
PSA | 117.96000 |
LogP | 4.74540 |
~% (2R)-2-(3-chlor... 625114-41-2 |
文献:Daniewski, Andrzej Robert; Liu, Wen; Radinov, Roumen Nikolaev Patent: US2007/244129 A1, 2007 ; Location in patent: Page/Page column 5; 7; 10 ; US 20070244129 A1 |
~44% (2R)-2-(3-chlor... 625114-41-2 |
文献:Sarabu, Ramakanth; Bizzarro, Fred T.; Corbett, Wendy L.; Dvorozniak, Mark T.; Geng, Wanping; Grippo, Joseph F.; Haynes, Nancy-Ellen; Hutchings, Stanley; Garofalo, Lisa; Guertin, Kevin R.; Hilliard, Darryl W.; Kabat, Marek; Kester, Robert F.; Ka, Wang; Liang, Zhenmin; Mahaney, Paige E.; Marcus, Linda; Matschinsky, Franz M.; Moore, David; Racha, Jagdish; Radinov, Roumen; Ren, Yi; Qi, Lida; Pignatello, Michael; Spence, Cheryl L.; Steele, Thomas; Tengi, John; Grimsby, Joseph Journal of Medicinal Chemistry, 2012 , vol. 55, # 16 p. 7021 - 7036 |
~% (2R)-2-(3-chlor... 625114-41-2 |
文献:Sarabu, Ramakanth; Bizzarro, Fred T.; Corbett, Wendy L.; Dvorozniak, Mark T.; Geng, Wanping; Grippo, Joseph F.; Haynes, Nancy-Ellen; Hutchings, Stanley; Garofalo, Lisa; Guertin, Kevin R.; Hilliard, Darryl W.; Kabat, Marek; Kester, Robert F.; Ka, Wang; Liang, Zhenmin; Mahaney, Paige E.; Marcus, Linda; Matschinsky, Franz M.; Moore, David; Racha, Jagdish; Radinov, Roumen; Ren, Yi; Qi, Lida; Pignatello, Michael; Spence, Cheryl L.; Steele, Thomas; Tengi, John; Grimsby, Joseph Journal of Medicinal Chemistry, 2012 , vol. 55, # 16 p. 7021 - 7036 |
~% (2R)-2-(3-chlor... 625114-41-2 |
文献:Sarabu, Ramakanth; Bizzarro, Fred T.; Corbett, Wendy L.; Dvorozniak, Mark T.; Geng, Wanping; Grippo, Joseph F.; Haynes, Nancy-Ellen; Hutchings, Stanley; Garofalo, Lisa; Guertin, Kevin R.; Hilliard, Darryl W.; Kabat, Marek; Kester, Robert F.; Ka, Wang; Liang, Zhenmin; Mahaney, Paige E.; Marcus, Linda; Matschinsky, Franz M.; Moore, David; Racha, Jagdish; Radinov, Roumen; Ren, Yi; Qi, Lida; Pignatello, Michael; Spence, Cheryl L.; Steele, Thomas; Tengi, John; Grimsby, Joseph Journal of Medicinal Chemistry, 2012 , vol. 55, # 16 p. 7021 - 7036 |
~% (2R)-2-(3-chlor... 625114-41-2 |
文献:Sarabu, Ramakanth; Bizzarro, Fred T.; Corbett, Wendy L.; Dvorozniak, Mark T.; Geng, Wanping; Grippo, Joseph F.; Haynes, Nancy-Ellen; Hutchings, Stanley; Garofalo, Lisa; Guertin, Kevin R.; Hilliard, Darryl W.; Kabat, Marek; Kester, Robert F.; Ka, Wang; Liang, Zhenmin; Mahaney, Paige E.; Marcus, Linda; Matschinsky, Franz M.; Moore, David; Racha, Jagdish; Radinov, Roumen; Ren, Yi; Qi, Lida; Pignatello, Michael; Spence, Cheryl L.; Steele, Thomas; Tengi, John; Grimsby, Joseph Journal of Medicinal Chemistry, 2012 , vol. 55, # 16 p. 7021 - 7036 |
~% (2R)-2-(3-chlor... 625114-41-2 |
文献:Sarabu, Ramakanth; Bizzarro, Fred T.; Corbett, Wendy L.; Dvorozniak, Mark T.; Geng, Wanping; Grippo, Joseph F.; Haynes, Nancy-Ellen; Hutchings, Stanley; Garofalo, Lisa; Guertin, Kevin R.; Hilliard, Darryl W.; Kabat, Marek; Kester, Robert F.; Ka, Wang; Liang, Zhenmin; Mahaney, Paige E.; Marcus, Linda; Matschinsky, Franz M.; Moore, David; Racha, Jagdish; Radinov, Roumen; Ren, Yi; Qi, Lida; Pignatello, Michael; Spence, Cheryl L.; Steele, Thomas; Tengi, John; Grimsby, Joseph Journal of Medicinal Chemistry, 2012 , vol. 55, # 16 p. 7021 - 7036 |
~% (2R)-2-(3-chlor... 625114-41-2 |
文献:Sarabu, Ramakanth; Bizzarro, Fred T.; Corbett, Wendy L.; Dvorozniak, Mark T.; Geng, Wanping; Grippo, Joseph F.; Haynes, Nancy-Ellen; Hutchings, Stanley; Garofalo, Lisa; Guertin, Kevin R.; Hilliard, Darryl W.; Kabat, Marek; Kester, Robert F.; Ka, Wang; Liang, Zhenmin; Mahaney, Paige E.; Marcus, Linda; Matschinsky, Franz M.; Moore, David; Racha, Jagdish; Radinov, Roumen; Ren, Yi; Qi, Lida; Pignatello, Michael; Spence, Cheryl L.; Steele, Thomas; Tengi, John; Grimsby, Joseph Journal of Medicinal Chemistry, 2012 , vol. 55, # 16 p. 7021 - 7036 |
~% (2R)-2-(3-chlor... 625114-41-2 |
文献:Sarabu, Ramakanth; Bizzarro, Fred T.; Corbett, Wendy L.; Dvorozniak, Mark T.; Geng, Wanping; Grippo, Joseph F.; Haynes, Nancy-Ellen; Hutchings, Stanley; Garofalo, Lisa; Guertin, Kevin R.; Hilliard, Darryl W.; Kabat, Marek; Kester, Robert F.; Ka, Wang; Liang, Zhenmin; Mahaney, Paige E.; Marcus, Linda; Matschinsky, Franz M.; Moore, David; Racha, Jagdish; Radinov, Roumen; Ren, Yi; Qi, Lida; Pignatello, Michael; Spence, Cheryl L.; Steele, Thomas; Tengi, John; Grimsby, Joseph Journal of Medicinal Chemistry, 2012 , vol. 55, # 16 p. 7021 - 7036 |
~% (2R)-2-(3-chlor... 625114-41-2 |
文献:Sarabu, Ramakanth; Bizzarro, Fred T.; Corbett, Wendy L.; Dvorozniak, Mark T.; Geng, Wanping; Grippo, Joseph F.; Haynes, Nancy-Ellen; Hutchings, Stanley; Garofalo, Lisa; Guertin, Kevin R.; Hilliard, Darryl W.; Kabat, Marek; Kester, Robert F.; Ka, Wang; Liang, Zhenmin; Mahaney, Paige E.; Marcus, Linda; Matschinsky, Franz M.; Moore, David; Racha, Jagdish; Radinov, Roumen; Ren, Yi; Qi, Lida; Pignatello, Michael; Spence, Cheryl L.; Steele, Thomas; Tengi, John; Grimsby, Joseph Journal of Medicinal Chemistry, 2012 , vol. 55, # 16 p. 7021 - 7036 |
Piragliatin |