氟甲睾酮结构式
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常用名 | 氟甲睾酮 | 英文名 | Fluoxymesterone |
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CAS号 | 76-43-7 | 分子量 | 336.441 | |
密度 | 1.2±0.1 g/cm3 | 沸点 | 474.2±45.0 °C at 760 mmHg | |
分子式 | C20H29FO3 | 熔点 | 240 °C | |
MSDS | N/A | 闪点 | 240.6±28.7 °C | |
符号 |
GHS02, GHS07, GHS08 |
信号词 | Danger |
氟甲睾酮用途Fluoxymesterone is an Androgen. The mechanism of action of fluoxymesterone is as an Androgen Receptor Agonist. |
中文名 | 氟甲睾酮 |
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英文名 | Fluoxymesterone |
中文别名 | 氟羟甲基睾酮 | 氟羟甲基睾丸素 | 龙坦特伦 |
英文别名 | 更多 |
密度 | 1.2±0.1 g/cm3 |
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沸点 | 474.2±45.0 °C at 760 mmHg |
熔点 | 240 °C |
分子式 | C20H29FO3 |
分子量 | 336.441 |
闪点 | 240.6±28.7 °C |
精确质量 | 336.210083 |
PSA | 57.53000 |
LogP | 2.17 |
外观性状 | 白色至淡黄色晶体粉末 |
蒸汽压 | 0.0±2.7 mmHg at 25°C |
折射率 | 1.562 |
储存条件 | 密封贮藏,储存在阴凉、干燥地方。 |
稳定性 | 与强氧化剂反应。 |
水溶解性 | NEGLIGIBLE |
计算化学 | 1.疏水参数计算参考值(XlogP):无 2.氢键供体数量:2 3.氢键受体数量:4 4.可旋转化学键数量:0 5.互变异构体数量:5 6.拓扑分子极性表面积57.5 7.重原子数量:24 8.表面电荷:0 9.复杂度:630 10.同位素原子数量:0 11.确定原子立构中心数量:7 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1 |
更多 | 1. 性状:白色无味粉末 2. 密度(g/mL,25℃):未确定 3. 相对蒸汽密度(g/mL,空气=1):未确定 4. 熔点(ºC):240 5. 沸点(ºC,常压):未确定 6. 沸点(ºC,5.2kPa):未确定 7. 折射率:未确定 8. 闪点(ºC):未确定 9. 比旋光度(º, C=1,乙醇):104 10. 自燃点或引燃温度(ºC):未确定 11. 蒸气压(kPa,20ºC):未确定 12. 饱和蒸气压(kPa,20ºC):未确定 13. 燃烧热(KJ/mol):未确定 14. 临界温度(ºC):未确定 15. 临界压力(KPa):未确定 16. 油水(辛醇/水)分配系数的对数值:未确定 17. 爆炸上限(%,V/V):未确定 18. 爆炸下限(%,V/V):未确定 19. 溶解性:微溶于水 |
符号 |
GHS02, GHS07, GHS08 |
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信号词 | Danger |
危害声明 | H225-H315-H360FD |
补充危害声明 | May form explosive peroxides. |
警示性声明 | P201-P210-P280-P308 + P313-P370 + P378-P403 + P235 |
危害码 (欧洲) | Xn: Harmful; |
风险声明 (欧洲) | R63 |
安全声明 (欧洲) | S22-S36-S24/25 |
危险品运输编码 | UN2252 - class 3 - PG 2 - 1,2-Dimethoxyethane solution |
WGK德国 | 3 |
RTECS号 | BV8390000 |
海关编码 | 2937290018 |
~% 氟甲睾酮 76-43-7 |
文献:Journal of the American Chemical Society, , vol. 78, p. 500 US2793218 , ; |
~% 氟甲睾酮 76-43-7 |
文献:Journal of the American Chemical Society, , vol. 78, p. 500 US2793218 , ; |
~% 氟甲睾酮 76-43-7 |
文献:Journal of the American Chemical Society, , vol. 78, p. 500 |
氟甲睾酮上游产品 3 | |
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氟甲睾酮下游产品 1 | |
海关编码 | 2937290018 |
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Rat liver lysosomal and mitochondrial activities are modified by anabolic-androgenic steroids.
Med. Sci Sports Exerc. 31 , 243, (1999) The aim of this study was to examine the separate and combined effects of an 8-wk treatment with high doses of 17alpha-alkylated anabolic-androgenic steroids (AAS) and exercise training on selected ly... |
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Biotransformation of 17-alkyl steroids in the equine: high-performance liquid chromatography-mass spectrometric and gas chromatography-mass spectrometric analysis of fluoxymesterone metabolites in urine samples.
J. Chromatogr. B. Biomed. Sci. Appl. 704 , 119, (1997) In this study the equine metabolism of fluoxymesterone (9alpha-fluoro-11beta-17beta-dihydroxy-17alpha-meth ylandrost-4-ene-3-one) given orally has been investigated. The parent material was not detect... |
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Comparison of chemotherapy with chemohormonal therapy as first-line therapy for metastatic, hormone-sensitive breast cancer: An Eastern Cooperative Oncology Group study.
J. Clin. Oncol. 18(2) , 262-6, (2000) Although hormonal therapy represents standard therapy for metastatic hormone-sensitive disease, many patients receive initial chemotherapy because of the location, bulk, or aggressiveness of their dis... |
11b,17b-Dihydroxy-9a-fluoro-17a-methyl-4-androsten-3-one |
(8S,9R,10S,11S,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13,17-trimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one |
Testosterone, 9-fluoro-11β-hydroxy-17-methyl- |
9a-Fluoro-11b-hydroxy-17a-methyltestosterone |
MFCD00010480 |
9α-Fluoro-11β-hydroxy-17-methyltestosterone |
(8S,9R,10S,11S,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13,17-trimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one |
Androst-4-en-3-one, 9-fluoro-11β,17β-dihydroxy-17-methyl- |
Halotestin |
EINECS 200-961-8 |
Androst-4-en-3-one, 9-fluoro-11,17-dihydroxy-17-methyl-, (11β,17β)- |
fluoxymesterone |
(8S,9R,10S,11S,13S,14S,17S)-9-Fluor-11,17-dihydroxy-10,13,17-trimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-on |
(11β,17β)-9-Fluoro-11,17-dihydroxy-17-methylandrost-4-en-3-one |
(8S,9R,10S,11S,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13,17-triméthyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tétradécahydro-3H-cyclopenta[a]phénanthrén-3-one |