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氟甲睾酮

更新时间:2024-01-02 13:16:17

氟甲睾酮结构式
氟甲睾酮结构式
品牌特惠专场
常用名 氟甲睾酮 英文名 Fluoxymesterone
CAS号 76-43-7 分子量 336.441
密度 1.2±0.1 g/cm3 沸点 474.2±45.0 °C at 760 mmHg
分子式 C20H29FO3 熔点 240 °C
MSDS N/A 闪点 240.6±28.7 °C
符号 GHS02 GHS07 GHS08
GHS02, GHS07, GHS08
信号词 Danger

 氟甲睾酮用途


Fluoxymesterone is an Androgen. The mechanism of action of fluoxymesterone is as an Androgen Receptor Agonist.

 氟甲睾酮名称

中文名 氟甲睾酮
英文名 Fluoxymesterone
中文别名 氟羟甲基睾酮 | 氟羟甲基睾丸素 | 龙坦特伦
英文别名 更多

 氟甲睾酮物理化学性质

密度 1.2±0.1 g/cm3
沸点 474.2±45.0 °C at 760 mmHg
熔点 240 °C
分子式 C20H29FO3
分子量 336.441
闪点 240.6±28.7 °C
精确质量 336.210083
PSA 57.53000
LogP 2.17
外观性状 白色至淡黄色晶体粉末
蒸汽压 0.0±2.7 mmHg at 25°C
折射率 1.562
储存条件

密封贮藏,储存在阴凉、干燥地方。

稳定性

与强氧化剂反应。

水溶解性 NEGLIGIBLE
计算化学

1.疏水参数计算参考值(XlogP):无

2.氢键供体数量:2

3.氢键受体数量:4

4.可旋转化学键数量:0

5.互变异构体数量:5

6.拓扑分子极性表面积57.5

7.重原子数量:24

8.表面电荷:0

9.复杂度:630

10.同位素原子数量:0

11.确定原子立构中心数量:7

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

更多

1. 性状:白色无味粉末

2. 密度(g/mL,25℃):未确定

3. 相对蒸汽密度(g/mL,空气=1):未确定

4. 熔点(ºC):240

5. 沸点(ºC,常压):未确定

6. 沸点(ºC,5.2kPa):未确定

7. 折射率:未确定

8. 闪点(ºC):未确定

9. 比旋光度(º, C=1,乙醇):104

10. 自燃点或引燃温度(ºC):未确定

11. 蒸气压(kPa,20ºC):未确定

12. 饱和蒸气压(kPa,20ºC):未确定

13. 燃烧热(KJ/mol):未确定

14. 临界温度(ºC):未确定

15. 临界压力(KPa):未确定

16. 油水(辛醇/水)分配系数的对数值:未确定

17. 爆炸上限(%,V/V):未确定

18. 爆炸下限(%,V/V):未确定

19. 溶解性:微溶于水

 氟甲睾酮MSDS

 氟甲睾酮毒性和生态

 氟甲睾酮安全信息

符号 GHS02 GHS07 GHS08
GHS02, GHS07, GHS08
信号词 Danger
危害声明 H225-H315-H360FD
补充危害声明 May form explosive peroxides.
警示性声明 P201-P210-P280-P308 + P313-P370 + P378-P403 + P235
危害码 (欧洲) Xn: Harmful;
风险声明 (欧洲) R63
安全声明 (欧洲) S22-S36-S24/25
危险品运输编码 UN2252 - class 3 - PG 2 - 1,2-Dimethoxyethane solution
WGK德国 3
RTECS号 BV8390000
海关编码 2937290018

 氟甲睾酮合成线路

~%

氟甲睾酮结构式

氟甲睾酮

76-43-7

文献:Journal of the American Chemical Society, , vol. 78, p. 500 US2793218 , ;

~%

氟甲睾酮结构式

氟甲睾酮

76-43-7

文献:Journal of the American Chemical Society, , vol. 78, p. 500 US2793218 , ;

~%

氟甲睾酮结构式

氟甲睾酮

76-43-7

文献:Journal of the American Chemical Society, , vol. 78, p. 500

 氟甲睾酮上下游产品

氟甲睾酮上游产品  3

氟甲睾酮下游产品  1

 氟甲睾酮海关

海关编码 2937290018

 氟甲睾酮文献25

更多文献
Rat liver lysosomal and mitochondrial activities are modified by anabolic-androgenic steroids.

Med. Sci Sports Exerc. 31 , 243, (1999)

The aim of this study was to examine the separate and combined effects of an 8-wk treatment with high doses of 17alpha-alkylated anabolic-androgenic steroids (AAS) and exercise training on selected ly...

Biotransformation of 17-alkyl steroids in the equine: high-performance liquid chromatography-mass spectrometric and gas chromatography-mass spectrometric analysis of fluoxymesterone metabolites in urine samples.

J. Chromatogr. B. Biomed. Sci. Appl. 704 , 119, (1997)

In this study the equine metabolism of fluoxymesterone (9alpha-fluoro-11beta-17beta-dihydroxy-17alpha-meth ylandrost-4-ene-3-one) given orally has been investigated. The parent material was not detect...

Comparison of chemotherapy with chemohormonal therapy as first-line therapy for metastatic, hormone-sensitive breast cancer: An Eastern Cooperative Oncology Group study.

J. Clin. Oncol. 18(2) , 262-6, (2000)

Although hormonal therapy represents standard therapy for metastatic hormone-sensitive disease, many patients receive initial chemotherapy because of the location, bulk, or aggressiveness of their dis...

 氟甲睾酮英文别名

11b,17b-Dihydroxy-9a-fluoro-17a-methyl-4-androsten-3-one
(8S,9R,10S,11S,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13,17-trimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Testosterone, 9-fluoro-11β-hydroxy-17-methyl-
9a-Fluoro-11b-hydroxy-17a-methyltestosterone
MFCD00010480
9α-Fluoro-11β-hydroxy-17-methyltestosterone
(8S,9R,10S,11S,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13,17-trimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
Androst-4-en-3-one, 9-fluoro-11β,17β-dihydroxy-17-methyl-
Halotestin
EINECS 200-961-8
Androst-4-en-3-one, 9-fluoro-11,17-dihydroxy-17-methyl-, (11β,17β)-
fluoxymesterone
(8S,9R,10S,11S,13S,14S,17S)-9-Fluor-11,17-dihydroxy-10,13,17-trimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-on
(11β,17β)-9-Fluoro-11,17-dihydroxy-17-methylandrost-4-en-3-one
(8S,9R,10S,11S,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13,17-triméthyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tétradécahydro-3H-cyclopenta[a]phénanthrén-3-one
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