氯环嗪结构式
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常用名 | 氯环嗪 | 英文名 | Di-Paralene |
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CAS号 | 82-93-9 | 分子量 | 300.82600 | |
密度 | N/A | 沸点 | 137-145ºC at 0.1-0.15 MM HG | |
分子式 | C18H21ClN2 | 熔点 | N/A | |
MSDS | 中文版 美版 | 闪点 | N/A | |
符号 |
GHS07, GHS09 |
信号词 | Warning |
氯环嗪用途Chlorcyclizine is a first-generation antihistamine of the phenylpiperazine class marketed in the United States and certain other countries. It is used primarily to treat allergy symptoms such as rhinitis, urticaria, and pruritus, and may also be used as an antiemetic. In addition to its antihistamine effects, chlorcyclizine also has some anticholinergic, antiserotonergic, and local anesthetic properties. It also has been studied as a potential treatment for hepatitis C. |
中文名 | 氯环嗪 |
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英文名 | 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine |
中文别名 | 氯苯甲嗪 |
英文别名 | 更多 |
沸点 | 137-145ºC at 0.1-0.15 MM HG |
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分子式 | C18H21ClN2 |
分子量 | 300.82600 |
精确质量 | 300.13900 |
PSA | 6.48000 |
LogP | 3.55260 |
储存条件 | 库房低温通风干燥 |
计算化学 | 1.疏水参数计算参考值(XlogP):无 2.氢键供体数量:0 3.氢键受体数量:2 4.可旋转化学键数量:3 5.互变异构体数量:无 6.拓扑分子极性表面积:6.5 7.重原子数量:21 8.表面电荷:0 9.复杂度:300 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:1 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1 |
符号 |
GHS07, GHS09 |
---|---|
信号词 | Warning |
危害声明 | H302-H400 |
警示性声明 | P301 + P312 + P330 |
危险品运输编码 | UN 3077 9 / PGIII |
海关编码 | 2933599090 |
~54% 氯环嗪 82-93-9 |
文献:Sengmany, Stephane; Le Gall, Erwan; Le Jean, Cedric; Troupel, Michel; Nedelec, Jean-Yves Tetrahedron, 2007 , vol. 63, # 18 p. 3672 - 3681 |
~% 氯环嗪 82-93-9 |
文献:Journal of the American Chemical Society, , vol. 71, p. 2731,2732 Journal of Organic Chemistry, , vol. 14, p. 775,777, 779 |
~34% 氯环嗪 82-93-9 |
文献:Sengmany, Stephane; Le Gall, Erwan; Le Jean, Cedric; Troupel, Michel; Nedelec, Jean-Yves Tetrahedron, 2007 , vol. 63, # 18 p. 3672 - 3681 |
~% 氯环嗪 82-93-9 |
文献:Venkat Narsaiah; Narsimha Medicinal Chemistry Research, 2012 , vol. 21, # 4 p. 538 - 541 |
~% 氯环嗪 82-93-9 |
文献:Medicinal Chemistry Research, , vol. 21, # 4 p. 538 - 541 |
~% 氯环嗪 82-93-9 |
文献:Medicinal Chemistry Research, , vol. 21, # 4 p. 538 - 541 |
~% 氯环嗪 82-93-9 |
文献:Medicinal Chemistry Research, , vol. 21, # 4 p. 538 - 541 |
~% 氯环嗪 82-93-9 |
文献:US2861072 , ; |
海关编码 | 2933599090 |
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中文概述 | 2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
申报要素 | 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期 |
Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Trihistan |
Chlorcycline |
Chlorocycline |
Alergicide |
Histantine |
Diparalene |
1-(4-chloro-benzhydryl)-4-methyl-piperazine |
Histachlorazene |
chlorcyclizine |
Perazyl |
1-[(4-chlorophenyl)(phenyl)methyl]-4-methylpiperazine |
Chlorocyclizine |