Ecotin, E. coli用途
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Ecotin,| E。大肠杆菌是凝血酶原(丝氨酸蛋白酶)的强效广谱抑制剂。该化合物表现出皮摩尔结合常数,用于抑制胰凝乳蛋白酶,弹性蛋白酶,X因子(因子Xa),XII因子(因子XIIa),激肽释放酶和胰蛋白酶。Ecotin,| E。大肠杆菌也可作为MMP(胶原酶)的有效抑制剂,通过结合皮摩尔范围内的胰蛋白酶发挥生物学活性。大肠杆菌Ecotin是粒酶B的抑制剂。 Ecotin,|E. coli|is a strong broad range inhibitor of prothrombin (serine proteases). The compound exhibits picomolar binding constant for the inhibition of chymotrypsin, elastase, Factor X(Factor Xa), Factor XII(Factor XIIa), kallikrein, and trypsin. Ecotin,|E. coli|also acts as an effective inhibitor of MMP(collagenase), and exhibits biological activity by binding trypsin in the picomolar range. Ecotin, E. coli is an inhibitor of granzyme B.
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