2-Nitrobenzoic acid

2-Nitrobenzoic acid Structure
2-Nitrobenzoic acid structure
Common Name 2-Nitrobenzoic acid
CAS Number 552-16-9 Molecular Weight 167.12
Density 1.5±0.1 g/cm3 Boiling Point 340.7±25.0 °C at 760 mmHg
Molecular Formula C7H5NO4 Melting Point 146-148 °C(lit.)
MSDS Chinese USA Flash Point 157.5±11.6 °C

Cranberry flavonoids prevent toxic rat liver mitochondrial damage in vivo and scavenge free radicals in vitro.

Cell Biochem. Funct. 33 , 202-10, (2015)

The present study was undertaken for further elucidation of the mechanisms of flavonoid biological activity, focusing on the antioxidative and protective effects of cranberry flavonoids in free radical-generating systems and those on mitochondrial ultrastruct...

Pd-Ir Core-Shell Nanocubes: A Type of Highly Efficient and Versatile Peroxidase Mimic.

ACS Nano 9 , 9994-10004, (2015)

Peroxidase mimics with dimensions on the nanoscale have received great interest as emerging artificial enzymes for biomedicine and environmental protection. While a variety of peroxidase mimics have been actively developed recently, limited progress has been ...

Targeted Delivery of 5-fluorouracil with Monoclonal Antibody Modified Bovine Serum Albumin Nanoparticles.

Iran. J. Pharm. Res. 14(2) , 395-405, (2015)

Herein, 1F2, an anti-HER2 monoclonal antibody (mAb), was covalently coupled to the surface of 5-Fluorouracil (5-FU) loaded bovine serum albumin (BSA) nanoparticles. Concerning two different crosslinkers for conjugation of 1F2, Maleimide-poly (ethylene glycol)...

Green tea polyphenol (-)-epigallocatechin-3-gallate triggered hepatotoxicity in mice: responses of major antioxidant enzymes and the Nrf2 rescue pathway.

Toxicol. Appl. Pharmacol. 283(1) , 65-74, (2015)

(-)-Epigallocatechin-3-gallate (EGCG), a constituent of green tea, has been suggested to have numerous health-promoting effects. On the other hand, high-dose EGCG is able to evoke hepatotoxicity. In the present study, we elucidated the responses of hepatic ma...

Protective Effects of Melatonin against Cyclophosphamide-induced Oxidative Lung Toxicity in Mice.

Drug Res. (Stuttg.) 65 , 281-6, (2015)

This study was undertaken to evaluate the protective effects of melatonin against cyclophosphamide (CP)-induced oxidative lung toxicity in mice. Mice were pre-treated with various doses of melatonin for 7 consecutive days and were then injected with CP (200 m...

Fermentation of Green Tea with 2% Aquilariae lignum Increases the Anti-Diabetic Activity of Green Tea Aqueous Extracts in the High Fat-Fed Mouse.

Nutrients 7 , 9046-78, (2015)

Anti-diabetic effects on the metabolomic differences between green tea (GT) and Aquilariae lignum-fermented green tea (fGT) were investigated in the high fat-fed mouse. To prove the differences, hypoglycemic (blood glucose, insulin and glycated hemoglobin lev...

Methamidophos alters sperm function and DNA at different stages of spermatogenesis in mice.

Toxicol. Appl. Pharmacol. 279(3) , 391-400, (2014)

Methamidophos (MET) is a highly toxic organophosphate (OP) pesticide that is widely used in developing countries. MET has male reproductive effects, including decreased fertility. We evaluated MET effects on sperm quality, fertilization and DNA integrity, exp...

Intracellular ROS Generation Mediates Maleimide-induced Cytotoxicity in Leukemia Cells.

Anticancer Agents Med. Chem. 15 , 1164-73, (2015)

Maleimides consist of an important class of compounds easily synthesized with multiple functional group modification that provides expressive pharmacological properties including, antitumoral activity, mediated mainly by oxidative stress. For this reason, the...

CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb- and paraquat-treated rat polymorphonuclear leukocytes.

Mol. Cell Biochem. 393(1-2) , 209-22, (2014)

Cytochrome P4502E1 (CYP2E1), glutathione-S-transferase A4-4 (GSTA4-4), and inducible nitric oxide synthase (iNOS) are implicated in maneb- and paraquat-induced toxicity leading to various pathological conditions. The study aimed to investigate the role of CYP...

Purple grape juice supplementation in smokers and antioxidant status according to different types of GST polymorphisms.

J. Clin. Biochem. Nutr. 56(1) , 49-56, (2015)

DNA damages and antioxidant status was assessed after 8 weeks of purple grape juice supplementation in male smokers depending on the glutathione S-transferase polymorphisms. Ninety-five smokers consumed 480 ml of purple grape juice for 8 weeks. The blood samp...