10.1038/nrmicro.2017.67

2017-07-17

Legionella pneumophila and Coxiella burnetii are two evolutionarily related intracellular pathogens that use the Dot/Icm type IV secretion system to translocate effectors into host cells. These effectors are essential for the establishment of membrane-bound c...

10.1038/nrmicro.2017.82

2017-07-13

The skin microbiota affects wound healing, inflammatory and immune responses to infections, and chronic skin diseases. Gimblet et al. investigated the role of the skin microbiota in cutaneous leishmaniasis and found that infection with Leishmania spp. parasit...

10.1038/nrmicro.2017.83

2017-07-13

Influenza viruses, similarly to other viruses, rapidly acquire de novo mutations when they replicate within their host cells.However, how the emergence of viral variants in the host is reflected at a global scale is still poorly understood. In a new study, Xu...

10.1038/nrmicro.2017.84

2017-07-13

Many bacteria have primitive proteinaceous organelles that are known as bacterial microcompartments (BMCs). All BMCs share a common architecture, with a selectively permeable protein shell that encapsulates different metabolic enzymes. Although detailed struc...

10.1038/nrmicro.2017.80

2017-07-10

This study presents cryo-electron microscopy structures of the type I-E Cascade and provides insights into PAM-dependent R-loop formation, Cas3 recruitment and substrate handover.

10.1038/nrmicro.2017.81

2017-07-10

In this study, Patel, White et al. discover that the hepatitis B virus pre-genome RNA contains specific nucleotide motifs that mediate interactions with the viral capsid protein to drive nucleocapsid assembly.

10.1038/nrmicro.2017.78

2017-07-10

This month's Genome Watch highlights how sequencing the genomes of multiple bacterial isolates from humans and animal infection models has revealed the presence of mutations that might represent adaptations for persistence in the host.

10.1038/nrmicro.2017.78

2017-07-10

This month's Genome Watch highlights how sequencing the genomes of multiple bacterial isolates from humans and animal infection models has revealed the presence of mutations that might represent adaptations for persistence in the host.

10.1038/nrmicro.2017.80

2017-07-10

This study presents cryo-electron microscopy structures of the type I-E Cascade and provides insights into PAM-dependent R-loop formation, Cas3 recruitment and substrate handover.

10.1038/nrmicro.2017.81

2017-07-10

In this study, Patel, White et al. discover that the hepatitis B virus pre-genome RNA contains specific nucleotide motifs that mediate interactions with the viral capsid protein to drive nucleocapsid assembly.