10.1038/s41551-017-0096

2017-07-11

The physiological relevance of Matrigel as a cell-culture substrate and in angiogenesis assays is often called into question. Here, we describe an array-based method for the identification of synthetic hydrogels that promote the formation of robust in vitro v...

10.1038/s41551-017-0102

2017-07-11

Ageing: Biomarkers get physical Nature Biomedical Engineering, Published online: 11 July 2017; doi:10.1038/s41551-017-0102 Cellular biophysical features are identified as predictive biomarkers of ageing.

10.1038/s41551-017-0098

2017-07-11

Genetic engineering: Lassoing genomic libraries Nature Biomedical Engineering, Published online: 11 July 2017; doi:10.1038/s41551-017-0098 Long single-stranded DNA probes enable the capture and multiplexed cloning of DNA at the megabase scale.

10.1038/s41551-017-0101

2017-07-11

Intraoperative histology: Lightning 3D histopathology Nature Biomedical Engineering, Published online: 11 July 2017; doi:10.1038/s41551-017-0101 A light-sheet microscope offers fast three-dimensional imaging of intact clinical tissue samples over large fields...

10.1038/s41551-017-0097

2017-07-11

Synthetic biology: A probiotic probe for inflammation Nature Biomedical Engineering, Published online: 11 July 2017; doi:10.1038/s41551-017-0097 Genetically modified bacteria provide a long-lasting record of intestinal inflammation in mice.

10.1038/s41551-017-0100

2017-07-11

Cell migration: Arraying neutrophils in swarms Nature Biomedical Engineering, Published online: 11 July 2017; doi:10.1038/s41551-017-0100 Microscale arrays of protein–polysaccharide clusters enable the functional characterization of human-neutrophil migration...

10.1038/s41551-017-0093

2017-07-11

Ageing research has focused either on assessing organ- and tissue-based changes, such as lung capacity and cardiac function, or on changes at the molecular scale such as gene expression, epigenetic modifications and metabolism. Here, by using a cohort of 32 s...

10.1038/s41551-017-0103

2017-07-11

Challenge the impact factor Nature Biomedical Engineering, Published online: 11 July 2017; doi:10.1038/s41551-017-0103 When comparing journals using citation-based metrics, the percentage of highly cited papers is more informative than the average number of c...

10.1038/s41551-017-0094

2017-06-30

Neutrophil swarms protect healthy tissues by sealing off sites of infection. In the absence of swarming, microbial invasion of surrounding tissues can result in severe infections. Recent observations in animal models have shown that swarming requires rapid ne...

10.1038/s41551-017-0084

2017-06-26

For the 1.7 million patients per year in the US who receive a new cancer diagnosis, treatment decisions are largely based on histopathological specimen examinations. Unfortunately, the gold standard of slide-based microscopic pathology suffers from high inter...