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Metabolism and prebiotics activity of anthocyanins from black rice (Oryza sativa L.) in vitro
10.1371/journal.pone.0195754 2018-04-09 Anthocyanins are naturally active substances. In this study, anthocyanins from black rice were obtained by membrane filtration and column chromatography separation. Five anthocyanin monomers in black rice extract were identified by HPLC-MS/MS, and the major a... |
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Green tea extracts ameliorate high-fat diet–induced muscle atrophy in senescence-accelerated mouse prone-8 mice
10.1371/journal.pone.0195753 2018-04-09 Muscle atrophy (loss of skeletal muscle mass) causes progressive deterioration of skeletal function. Recently, excessive intake of fats was suggested to induce insulin resistance, followed by muscle atrophy. Green tea extracts (GTEs), which contain polyphenol... |
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Parkinson's disease-related non-motor features as risk factors for post-operative delirium in spinal surgery
10.1371/journal.pone.0195749 2018-04-09 Background The clinical features of postoperative delirium are similar to the core features of alpha synuclein-related cognitive disorders, such as Parkinson’s disease dementia (PDD) or dementia with Lewy bodies (DLB). Therefore, we hypothesized that the non-... |
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Increasing prevalence, molecular characterization and antifungal drug susceptibility of serial Candida auris isolates in Kuwait
10.1371/journal.pone.0195743 2018-04-09 Candida auris is an emerging yeast pathogen of global significance. Its multidrug-resistant nature and inadequacies of conventional identification systems pose diagnostic and therapeutic challenges. This study investigated occurrence of C. auris in clinical s... |
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Can a single pulse transcranial magnetic stimulation targeted to the motor cortex interrupt pain processing?
10.1371/journal.pone.0195739 2018-04-09 The modulatory role of the primary motor cortex (M1), reflected by an inhibitory effect of M1-stimulation on clinical pain, motivated us to deepen our understanding of M1’s role in pain modulation. We used Transcranial Magnetic Stimulation (TMS)-induced virtu... |
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Oxygen microbubbles improve radiotherapy tumor control in a rat fibrosarcoma model – A preliminary study
10.1371/journal.pone.0195667 2018-04-09 Cancer affects 39.6% of Americans at some point during their lifetime. Solid tumor microenvironments are characterized by a disorganized, leaky vasculature that promotes regions of low oxygenation (hypoxia). Tumor hypoxia is a key predictor of poor treatment ... |
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Mortality in long-distance running races in Sweden - 2007–2016
10.1371/journal.pone.0195626 2018-04-09 Background During the last decade, an increasing popularity of marathons has been seen. Although running has been shown to have considerable positive health effects, the risk of sudden death, most often due to sudden cardiac arrests, is also a risk runners ex... |
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Identification of G-quadruplex forming sequences in three manatee papillomaviruses
10.1371/journal.pone.0195625 2018-04-09 The Florida manatee (Trichechus manatus latirotris) is a threatened aquatic mammal in United States coastal waters. Over the past decade, the appearance of papillomavirus-induced lesions and viral papillomatosis in manatees has been a concern for those involv... |
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Approximating net interactions among rigid domains
10.1371/journal.pone.0195618 2018-04-09 Many physical simulations aim at evaluating the net interaction between two rigid bodies, resulting from the cumulative effect of pairwise interactions between their constituents. This is manifested particularly in biomolecular applications such as hierarchic... |
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Long-term exposure to ambient air pollutants and mental health status: A nationwide population-based cross-sectional study
10.1371/journal.pone.0195607 2018-04-09 There is a suspected but unproven association between long-term exposure to ambient air pollution and mental health. The aim of this study is to investigate the association between long-term exposure to ambient air pollution and subjective stress, depressive ... |