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Gold Nanoplate‐Enhanced Chemiluminescence and Macromolecular Shielding for Rapid Microbial Diagnostics
10.1002/adhm.201701506 2018-04-03 With the global rise of antimicrobial resistance, rapid screening and identification of low concentrations of microorganisms in less than 1 h becomes an urgent technological need for evidence‐based antibiotic therapy. Although many commercially available tech... |
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Mechanical Considerations for Electrospun Nanofibers in Tendon and Ligament Repair
10.1002/adhm.201701277 2018-03-30 Electrospun nanofibers possess unique qualities such as nanodiameter, high surface area to volume ratio, biomimetic architecture, and tunable chemical and electrical properties. Numerous studies have demonstrated the potential of nanofibrous architecture to d... |
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3D Interconnected Mesoporous Alumina with Loaded Hemoglobin as a Highly Active Electrochemical Biosensor for H2O2
10.1002/adhm.201800149 2018-03-27 Alumina is one of the most common and stable metal oxides in nature, which has been developed as a novel adsorbent in enrichment of biomolecules due to its excellent affinity to phosphor or amino groups. In this study, ordered mesoporous alumina (OMA) with in... |
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Toward Immunocompetent 3D Skin Models
10.1002/adhm.201701405 2018-03-15 3D human skin models provide a platform for toxicity testing, biomaterials evaluation, and investigation of fundamental biological processes. However, the majority of current in vitro models lack an inflammatory system, vasculature, and other characteristics ... |
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Current Concepts in Meniscus Tissue Engineering and Repair
10.1002/adhm.201701407 2018-03-15 The meniscus is the most commonly injured structure in the human knee. Meniscus deficiency has been shown to lead to advanced osteoarthritis (OA) due to abnormal mechanical forces, and replacement strategies for this structure have lagged behind other tissue ... |
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Nanofibered Gelatin‐Based Nonwoven Elasticity Promotes Epithelial Histogenesis
10.1002/adhm.201700895 2018-03-12 Regarding tissue regeneration, mechanics of biomaterials gains progressive importance. Therefore, this study reports on in situ crosslinked electrospun gelatin nonwoven mats (NWMs) whose distinct modulus of elasticity (ME) promotes epithelial tissue formation... |
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NanoTRAIL‐Oncology: A Strategic Approach in Cancer Research and Therapy
10.1002/adhm.201800053 2018-03-12 TRAIL is a member of the tumor necrosis factor superfamily that can largely trigger apoptosis in a wide variety of cancer cells, but not in normal cells. However, insufficient exposure to cancer tissues or cells and drug resistance has severely impeded the cl... |
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Carbon‐Dot‐Decorated TiO2 Nanotubes toward Photodynamic Therapy Based on Water‐Splitting Mechanism
10.1002/adhm.201800042 2018-03-12 The use of visible light to produce reactive oxygen species (ROS) from renewable water splitting is a highly promising means in photodynamic therapy (PDT). Up to date, diverse inorganic–organic hybrid materials developed as photosensitizers still undergo low ... |
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Sonochemistry‐Assembled Stimuli‐Responsive Polymer Microcapsules for Drug Delivery
10.1002/adhm.201701326 2018-03-12 Stimuli‐responsive polymer microcapsules (PMs) fabricated by the sonochemical method have emerged for developing useful drug delivery systems, and the latest developments are mainly focusing on the synthetic strategies and properties such as structure, size, ... |
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Biomaterial Scaffolds as Pre‐metastatic Niche Mimics Systemically Alter the Primary Tumor and Tumor Microenvironment
10.1002/adhm.201700903 2018-03-09 Primary tumor (PT) immune cells and pre‐metastatic niche (PMN) sites are critical to metastasis. Recently, synthetic biomaterial scaffolds used as PMN mimics are shown to capture both immune and metastatic tumor cells. Herein, studies are performed to investi... |