Metronidazole-d4 hydrochloride

Modify Date: 2024-01-10 13:55:18

Metronidazole-d4 hydrochloride Structure
Metronidazole-d4 hydrochloride structure
Common Name Metronidazole-d4 hydrochloride
CAS Number 1261397-74-3 Molecular Weight 211.639
Density N/A Boiling Point N/A
Molecular Formula C6H6D4ClN3O3 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS08
GHS08
Signal Word Warning

 Use of Metronidazole-d4 hydrochloride


Metronidazole-d4 hydrochloride is the deuterium labeled Metronidazole hydrochloride[1].

 Names

Name 2-(2-Methyl-5-nitro-1H-imidazol-1-yl)(2H4)ethanol hydrochloride (1:1)
Synonym More Synonyms

 Metronidazole-d4 hydrochloride Biological Activity

Description Metronidazole-d4 hydrochloride is the deuterium labeled Metronidazole hydrochloride[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

 Chemical & Physical Properties

Molecular Formula C6H6D4ClN3O3
Molecular Weight 211.639
Exact Mass 211.066177

 Safety Information

Symbol GHS08
GHS08
Signal Word Warning
Hazard Statements H351
Precautionary Statements P281
RIDADR NONH for all modes of transport

 Synonyms

1H-Imidazole-1-ethan-α,α,β,β-d4-ol, 2-methyl-5-nitro-, hydrochloride (1:1)
2-(2-Methyl-5-nitro-1H-imidazol-1-yl)(2H4)ethanol hydrochloride (1:1)