(2H24)Tetradecanedioic acid

Modify Date: 2024-01-11 15:20:16

(2H24)Tetradecanedioic acid Structure
(2H24)Tetradecanedioic acid structure
Common Name (2H24)Tetradecanedioic acid
CAS Number 130348-88-8 Molecular Weight 282.502
Density 1.0±0.1 g/cm3 Boiling Point 434.1±18.0 °C at 760 mmHg
Molecular Formula C14H2D24O4 Melting Point N/A
MSDS N/A Flash Point 230.5±17.7 °C

 Use of (2H24)Tetradecanedioic acid


Tetradecanedioic acid-d24 is the deuterium labeled Tetradecanedioic acid[1]. Tetradecanedioic acid is an endogenous metabolite and belongs to the class of organic compounds known as long-chain fatty acids. Tetradecanedioic acid can act as a candidate biomarker for organic anion-transporting polypeptide mediated drug-drug interactions[2].

 Names

Name 1,14-tetradecanedioic-d24 acid
Synonym More Synonyms

 (2H24)Tetradecanedioic acid Biological Activity

Description Tetradecanedioic acid-d24 is the deuterium labeled Tetradecanedioic acid[1]. Tetradecanedioic acid is an endogenous metabolite and belongs to the class of organic compounds known as long-chain fatty acids. Tetradecanedioic acid can act as a candidate biomarker for organic anion-transporting polypeptide mediated drug-drug interactions[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Santockyte R, et al. LC-MS/MS bioanalysis of plasma 1, 14-tetradecanedioic acid and 1, 16-hexadecanedioic acid as candidate biomarkers for organic anion-transporting polypeptide mediated drug-drug interactions. Bioanalysis. 2018 Sep 1;10(18):1473-1485.  

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 434.1±18.0 °C at 760 mmHg
Molecular Formula C14H2D24O4
Molecular Weight 282.502
Flash Point 230.5±17.7 °C
Exact Mass 282.333740
PSA 74.60000
LogP 3.99
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.475

 Synonyms

Tetradecanedioic-d acid
(H)Tetradecanedioic acid