Fmoc-Phe-OH-d8

Modify Date: 2024-01-20 16:29:24

Fmoc-Phe-OH-d8 Structure
Fmoc-Phe-OH-d8 structure
Common Name Fmoc-Phe-OH-d8
CAS Number 1353853-39-0 Molecular Weight 395.48
Density 1.3±0.1 g/cm3 Boiling Point 620.1±50.0 °C at 760 mmHg
Molecular Formula C24H13D8NO4 Melting Point N/A
MSDS N/A Flash Point 328.8±30.1 °C

 Use of Fmoc-Phe-OH-d8


Fmoc-Phe-OH-d8 is the deuterium labeled Fmoc-Phe-OH.

 Names

Name N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-(α,β,β,2,3,4,5,6-2H8)phenylalanine
Synonym More Synonyms

 Fmoc-Phe-OH-d8 Biological Activity

Description Fmoc-Phe-OH-d8 is the deuterium labeled Fmoc-Phe-OH.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 620.1±50.0 °C at 760 mmHg
Molecular Formula C24H13D8NO4
Molecular Weight 395.48
Flash Point 328.8±30.1 °C
Exact Mass 395.197266
LogP 5.41
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.633

 Synonyms

L-Phenylalanine-α,β,β,2,3,4,5,6-d8, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-(α,β,β,2,3,4,5,6-2H8)phenylalanine